HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1G12 monoclonal antibody

antibody to the N-domain of human angiotensin-converting enzyme for detection of ACE inhibitors in human blood

Also Known As:

mAb 1G12; monoclonal antibody 1G12

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        1G12 monoclonal antibody: 2
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        1G12 monoclonal antibody: 2
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        1G12 monoclonal antibody: 2

Experts

1.	Danilov, Sergei M: 1 article (01/2012)
2.	Garcia, Joe G N: 1 article (01/2012)
3.	Kost, Olga A: 1 article (01/2012)
4.	Petrov, Maxim N: 1 article (01/2012)
5.	Schwartz, David E: 1 article (01/2012)
6.	Shilo, Valery Y: 1 article (01/2012)
7.	Tarasov, Alexandr V: 1 article (01/2012)

Related Diseases

1.	Uremia 01/01/2012 - "Some patients with uremia due to ESRD exhibited significantly increased mAb 1G12 binding to blood ACE and increased ACE activity towards angiotensin I accompanied by reduced ACE inhibition by inhibitory mAbs and ACE inhibitors. "
2.	Chronic Kidney Failure (Chronic Renal Failure) 01/01/2012 - "The estimation of relative mAb 1G12 binding to blood ACE detects a subpopulation of ESRD patients with conformationally changed ACE, which activity is less suppressible by ACE inhibitors. " 01/01/2012 - "Some patients with uremia due to ESRD exhibited significantly increased mAb 1G12 binding to blood ACE and increased ACE activity towards angiotensin I accompanied by reduced ACE inhibition by inhibitory mAbs and ACE inhibitors. "
3.	Carcinoma (Carcinomatosis) 01/01/1991 - "These results show that human mAb 1G12 may be useful for the analysis of tumour-associated antigen of mammary carcinoma patients. " 01/01/1991 - "Tumour-associated antigens of mammary carcinomas recognized by human monoclonal antibody 1G12."

Related Drugs and Biologics

1.	Antigens
2.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
3.	Angiotensin I