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ethyl- 2- (N- p- chlorobenzyl- (2'- methyl))anilino- 4- oxo- 4,5- dihydrofuran- 3- carboxylate

induces apoptosis in human cervical cancer Ca Ski cells; structure in first source

Also Known As:

JOTO1007

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - ethyl-2-(N-p-chlorobenzyl-(2'-methyl))anilino-4-oxo-4,5-dihydrofuran-3-carboxylate: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - ethyl-2-(N-p-chlorobenzyl-(2'-methyl))anilino-4-oxo-4,5-dihydrofuran-3-carboxylate: 1

Experts

1.	Chung, Jing-Gung: 1 article (07/2009)
2.	Hsu, Shu-Chun: 1 article (07/2009)
3.	Huang, An-Cheng: 1 article (07/2009)
4.	Kuo, Chao-Lin: 1 article (07/2009)
5.	Lai, Kuang-Chi: 1 article (07/2009)
6.	Liao, Ching-Lung: 1 article (07/2009)
7.	Lin, Tsung-Ping: 1 article (07/2009)
8.	Lu, Hsu-Feng: 1 article (07/2009)
9.	Tang, Nou-Ying: 1 article (07/2009)
10.	Wu, Shin-Hwar: 1 article (07/2009)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 07/01/2009 - "Secondly, the effect of JOTO1007 on the levels of proteins associated with cell metastasis was examined using Western blotting. "
2.	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/01/2009 - "JOTO1007 (ethyl 2-[N-p-chlorobenzyl-(2'-methyl)] anilino-4-oxo-4,5-dihydrofuran -3-carboxylate) has anticancer effects in human cervical cancer Ca Ski cells. " 07/01/2009 - "Involvement of matrix metalloproteinases in the inhibition of cell invasion and migration through the inhibition of NF-[kappa]B by the new synthesized ethyl 2-[N-p-chlorobenzyl-(2'-methyl)]anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOTO1007) in human cervical cancer Ca ski cells."

Related Drugs and Biologics

1.	Matrix Metalloproteinases (MMPs)
2.	NF-kappa B (NF-kB)
3.	Proteins (Proteins, Gene)