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GB-115

Also Known As:

Ph(CH2)5CO-Gly-Trp-NH2

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - GB-115: 2

Experts

1.	Seredenin, S B: 2 articles (01/2019 - 03/2011)
2.	Dorofeeva, O A: 1 article (01/2019)
3.	Ivashkina, N Yu: 1 article (01/2019)
4.	Martyanov, V A: 1 article (01/2019)
5.	Metlina, M V: 1 article (01/2019)
6.	Minaev, S V: 1 article (01/2019)
7.	Neznamov, G G: 1 article (01/2019)
8.	Syunyakov, T S: 1 article (01/2019)
9.	Durnev, A D: 1 article (03/2011)
10.	Gudasheva, T A: 1 article (03/2011)

Related Diseases

1.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 03/01/2011 - "Intraperitoneal injection of GB-115 in a dose of 1 mg/kg to C57Bl/6 female mice with experimental autoimmune encephalomyelitis significantly alleviated the pathological symptoms, improved spontaneous locomotor activity, promoted recovery of thymus weight, and reduced edema and neutrophil infiltration of the perivascular space of the brain tissue. "
2.	Edema (Dropsy) 03/01/2011 - "Intraperitoneal injection of GB-115 in a dose of 1 mg/kg to C57Bl/6 female mice with experimental autoimmune encephalomyelitis significantly alleviated the pathological symptoms, improved spontaneous locomotor activity, promoted recovery of thymus weight, and reduced edema and neutrophil infiltration of the perivascular space of the brain tissue. "
3.	Inflammation (Inflammations) 03/01/2011 - "Anti-inflammatory effects of GB-115 compound (N-phenylhexanoyl-glycyl-L-tryptophan amide) injected intraperitoneally in doses of 0.1, 1, and 10 mg/kg were demonstrated on the model of ConA- and carrageenan-induced inflammation. "
4.	Anxiety Disorders (Anxiety Disorder) 01/01/2019 - "To evaluate anxiolytic action of GB-115, a low-affinity blocker of central cholecystokinin receptors, used in tablets in a dose of 1 mg for the treatment of patients with anxiety disorders in order to determine effective dose, safety, tolerability and efficacy in clinical settings. "

Related Drugs and Biologics

1.	Anti-Anxiety Agents (Anxiolytics)
2.	Tablets
3.	Cholecystokinin Receptors (Cholecystokinin Receptor)
4.	Carrageenan
5.	Amides
6.	glycyltryptophan

Related Therapies and Procedures

1.	Intraperitoneal Injections