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2- (5- (4- (2- hydroxyethyl)piperazin- 1- ylsulfonyl)- 2- n- propoxyphenyl)- 5- ethyl- 7- n- propyl- 3,5- dihydro- 4H- pyrrolo(3,2- d)pyrimidin- 4- one dihydrochloride

phosphodiesterase type V inhibitor; structure in first source

Also Known As:

SK3530; SK3530.2HCl

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - 2-(5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)-2-n-propoxyphenyl)-5-ethyl-7-n-propyl-3,5-dihydro-4H-pyrrolo(3,2-d)pyrimidin-4-one dihydrochloride: 3
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfones: 534
    - 2-(5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)-2-n-propoxyphenyl)-5-ethyl-7-n-propyl-3,5-dihydro-4H-pyrrolo(3,2-d)pyrimidin-4-one dihydrochloride: 3

Experts

1.	Cho, Sung-Dae: 1 article (11/2008)
2.	Choi, Changsun: 1 article (11/2008)
3.	Im, Gwang-Jin: 1 article (11/2008)
4.	Jung, Ji-Won: 1 article (11/2008)
5.	Jung, Ji-Youn: 1 article (11/2008)
6.	Kim, Byeong-Soo: 1 article (11/2008)
7.	Kim, Jong-Suk: 1 article (11/2008)
8.	Kim, Sang-Ki: 1 article (11/2008)
9.	Kim, So-Jung: 1 article (11/2008)
10.	Lee, Seung-Ho: 1 article (11/2008)

Related Diseases

1.	Spinal Cord Injuries (Spinal Cord Injury) 11/01/2008 - "The penile erection efficacy of a new phosphodiesterase type 5 inhibitor, mirodenafil (SK3530), in rabbits with acute spinal cord injury."
2.	Erectile Dysfunction 09/01/2008 - "Efficacy and safety of oral SK3530 for the treatment of erectile dysfunction in Korean men: a multicenter, randomized, double-blind, placebo-controlled, fixed dose, parallel group clinical trial." 09/01/2008 - "To evaluate the efficacy and safety of SK3530, a newly developed type 5 phosphodiesterase inhibitor (PDE5I), in Korean men with erectile dysfunction (ED). " 09/21/2007 - "5-Ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) is a new phosphodiesterase type-5 inhibitor currently undergoing a Phase III investigation for the treatment of male erectile dysfunction. "

Related Drugs and Biologics

1.	Phosphodiesterase 5 Inhibitors
2.	mirodenafil
3.	Type 5 Cyclic Nucleotide Phosphodiesterases
4.	Phosphoric Diester Hydrolases (Phosphodiesterases)
5.	Piperazine