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bis(2-hydroxybenzylidene)acetone

structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Acetone: 1775
    - bis(2-hydroxybenzylidene)acetone: 1
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        bis(2-hydroxybenzylidene)acetone: 1

Experts

1.	Bozak, Richard E: 1 article (01/2007)
2.	Cory, Ann H: 1 article (01/2007)
3.	Cory, Joseph G: 1 article (01/2007)
4.	Dinkova-Kostova, Albena T: 1 article (01/2007)
5.	Hicks, Ronald J: 1 article (01/2007)

Related Diseases

1.

01/08/2007 - "Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway."
01/08/2007 - "In our efforts to identify potent chemoprotective agents, we found that in rapidly growing murine leukemia cells (L1210) low concentrations (in the submicromolar range) of bis(2-hydroxybenzylidene)acetone markedly increased the activities of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) and glutathione reductase, and the levels of total glutathione, three markers of the phase 2 response. "

Related Drugs and Biologics

1.	Caspases
2.	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
3.	Glutathione Reductase (Glutathione-Disulfide Reductase)
4.	Glutathione (Reduced Glutathione)