GIFT15 protein

GIFT15 - GMCSF and IL-15 fusion transgene product; GMCSF - granulocyte macrophage colony-stimulating factor; defines a class of fusokine that mediates proangiogenic and immunosuppressive effects via aberrant signaling by the IL-15R in lymphomyeloid cells

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - GIFT15 protein: 1
  - Recombinant Proteins: 2754
    - Recombinant Fusion Proteins: 333
      - GIFT15 protein: 1
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - GIFT15 protein: 1
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - GIFT15 protein: 1

Experts

1.	Annabi, Borhane: 1 article (03/2007)
2.	François, Moïra: 1 article (03/2007)
3.	Galipeau, Jacques: 1 article (03/2007)
4.	Lejeune, Laurence: 1 article (03/2007)
5.	Rafei, Moutih: 1 article (03/2007)
6.	Wu, Jian Hui: 1 article (03/2007)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2007 - "Unexpectedly, tumor cells engineered to secrete GIFT15 protein led to suppression of natural killer (NK) and NKT-cell recruitment in vivo, suggesting an unanticipated immune-suppressive effect. "