arzanol

a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum; has antioxidant and cytotoxic activity; structure in first source

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Monti, Maria Chiara: 2 articles (01/2021 - 11/2018)
2.	Pollastro, Federica: 2 articles (11/2018 - 01/2011)
3.	Anand, Ruchika: 1 article (01/2021)
4.	Berleth, Niklas: 1 article (01/2021)
5.	Berning, Lena: 1 article (01/2021)
6.	Böhler, Philip: 1 article (01/2021)
7.	Ceccacci, Sara: 1 article (01/2021)
8.	Deitersen, Jana: 1 article (01/2021)
9.	Friedrich, Annabelle: 1 article (01/2021)
10.	Mendiburo, María José: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2021 - "Collectively, our results suggest arzanol as a valuable tool for autophagy research and as a lead compound for drug development in cancer therapy." 01/01/2013 - "Diversity of mechanisms of actions of arzanol may be useful in treatment of disease involving these inflammatory mediators such as autoimmune diseases and cancer. " 11/13/2018 - "Competitive affinity-based proteomics, DARTS, molecular docking, surface plasmon resonance and in vitro biological assays provided molecular mechanistic insights into the arzanol-enzyme interaction, qualifying this positive modulator of bGP for further studies in the realm of neurodegeneration and cancer."
2.	Mood Disorders (Mood Disorder) 10/01/2023 - "Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol."
3.	Pleurisy (Pleuritis) 01/15/2011 - "Arzanol potently suppressed the inflammatory response of the carrageenan-induced pleurisy in rats (3.6mg/kg, i.p.), with significantly reduced levels of PGE(2) in the pleural exudates. "
4.	Body Weight (Weight, Body) 10/01/2023 - "Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol."
5.	Urinary Bladder Neoplasms (Bladder Cancer) 01/01/2021 - "We further show that arzanol is able to sensitize RT-112 bladder cancer cells towards cisplatin (CDDP). "

Related Drugs and Biologics

1.	Enzymes
2.	Sirtuin 1
3.	Prostaglandins E
4.	Cisplatin (Platino)
5.	Carrageenan

Related Therapies and Procedures

1.	Therapeutics