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ATI 7505

Also Known As:

(3R)-1-azabicyclo(2.2.2)oct-3-yl 6-((3S,4R)-4-((4-amino-5-chloro-2-methoxybenzoyl)amino)-3-methoxy-1-piperidinyl)hexanoate; ATI-7505; ATI7505; naronapride

Networked: 6 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Camilleri, Michael: 2 articles (11/2019 - 06/2010)
2.	Black, Christopher J: 1 article (11/2019)
3.	Burr, Nicholas E: 1 article (11/2019)
4.	Ford, Alexander C: 1 article (11/2019)
5.	Luthra, Pavit: 1 article (11/2019)
6.	Quigley, Eamonn M M: 1 article (11/2019)
7.	Camilleri, M: 1 article (02/2014)
8.	Erwin, P: 1 article (02/2014)
9.	Kolar, G: 1 article (02/2014)
10.	Murad, M H: 1 article (02/2014)

Related Diseases

1.	Constipation 12/01/2009 - "The progress of this compound for treatment of chronic constipation, as well as competitor molecules such as ATI-7505 and TD-5108, will now be followed with interest as each attempts to differentiate themselves from each other. " 12/01/2022 - "Apart from prucalopride, approved in Europe for refractory chronic idiopathic constipation patients, the selective 5-HT4 agonists velusetrag and naronapride are in advanced development. " 02/01/2014 - "Systematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipation." 11/01/2019 - "We searched Medline, Embase, Embase Classic, and the Cochrane Central Register of Controlled Trials for randomised controlled trials published from inception to week 3 June, 2019, to identify randomised controlled trials assessing the efficacy of drugs (osmotic or stimulant laxatives, elobixibat, linaclotide, lubiprostone, mizagliflozin, naronapride, plecanatide, prucalopride, tegaserod, tenapanor, or velusetrag) in adults with chronic idiopathic constipation. "
2.	Gastroparesis 06/01/2013 - "A literature search was undertaken using the search terms: gastroparesis, diabetic gastroparesis, idiopathic gastroparesis, gastric emptying, prokinetic, metoclopramide, domperidone, erythromycin, motilin, alemcinal, KC11458, mitemcinal, ghrelin, TZP-101, TZP-102, RM-131, tegaserod, prucalopride, naronapride, velusetrag, levosulpiride, itopride, botulinum toxin, gastric electrical stimulation, Enterra. "
3.	Cardiac Arrhythmias (Arrythmia) 06/01/2010 - "We conducted a PubMed search using the following key words alone or in combination: 5-HT(4), safety, toxicity, pharmacokinetics, pharmacodynamics, clinical trial, cardiac, hERG, arrhythmia, potassium current, elderly, prucalopride, ATI-7505, and velusetrag (TD-5108), to review mechanisms of action, clinical efficacy, safety and tolerability of three new-generation 5-HT(4) receptor agonists. "

Related Drugs and Biologics

1.	TD-5108
2.	prucalopride
3.	tegaserod (Zelnorm)
4.	Lubiprostone
5.	plecanatide
6.	elobixibat
7.	linaclotide
8.	mizagliflozin
9.	tenapanor
10.	Serotonin 5-HT4 Receptor Agonists