resolvin E2

structure in first source; derivative of eicosapentaenoic acid in contrast to resolvin D that derives from docosahexaenoic acid

Also Known As:

(5S,6E,8Z,11Z,14Z,16E,18R)-5,18-dihydroxy-6,8,11,14,16-icosapentaenoic acid; RvE2 compound

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Serhan, Charles N: 2 articles (02/2022 - 05/2012)
2.	Libreros, Stephania: 1 article (02/2022)
3.	Nshimiyimana, Robert: 1 article (02/2022)
4.	Beckmann, Taylor G: 1 article (11/2018)
5.	Cebak, John E: 1 article (11/2018)
6.	Donohue, Michelle N: 1 article (11/2018)
7.	Johnson, Jason W: 1 article (11/2018)
8.	Miller, Lynda M J: 1 article (11/2018)
9.	Treece, MacKenzie: 1 article (11/2018)
10.	Wood, Paul L: 1 article (11/2018)

Related Diseases

1.	Peritonitis 05/01/2012 - "In this study, we report that resolvin E2 (RvE2) from eicosapentaenoic acid is endogenously produced during self-limited murine peritonitis in both the initiation and resolution phases. " 08/20/2009 - "The synthetic resolvin E2 proved to be biologically active in blocking neutrophil infiltration and reducing proinflammatory cytokines in the acute peritonitis model."
2.	Inflammation (Inflammations) 05/01/2012 - "Resolvin E2 formation and impact in inflammation resolution." 01/01/2022 - "Herein, we review the biosynthesis and functions of the E-series resolvins, namely resolvin E1 (the first n-3 resolvin identified), resolvin E2, resolvin E3 and resolvin E4 biosynthesized from their precursor eicosapentaenoic acid (EPA), and the critical role of total organic synthesis in confirming SPM complete stereochemistry, establishing their potent functions in resolution of inflammation, and novel structures. "
3.	Neoplasms (Cancer) 01/01/2023 - "A comprehensive lipidomic analysis also uncovered several potential pharmacodynamic (PD) lipid biomarkers, including resolvin E2, 9-HEPE, 12-HEPE and 18-HEPE, that were significantly correlated with tumor protection. "
4.	Conjunctivitis 11/21/2018 - "Results: Bovine pink eye resulted in dramatic elevations in tear fluid levels of the anti-inflammatory lipids resolvin E2, cyclic phosphatidic acid 16:0, and cyclic phosphatidic acid 18:0. "
5.	Asthma (Bronchial Asthma) 03/24/2023 - "Intra-Airway Treatment with Synthetic Lipoxin A4 and Resolvin E2 Mitigates Neonatal Asthma Triggered by Maternal Exposure to Environmental Particles."

Related Drugs and Biologics

1.	Eicosapentaenoic Acid
2.	Lipids
3.	Cytokines
4.	Biomarkers (Surrogate Marker)
5.	Phosphatidic Acids (Phosphatidic Acid)
6.	17,18-dihydroxyeicosapentaenoic acid
7.	cyclic phosphatidic acid 16:0
8.	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acid
9.	lipoxin A4