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NA-LMWH

structure in first source

Also Known As:

non-anticoagulant oxidized ultra-LMWH

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Glycosaminoglycans: 5640
    - Heparin: 24996
      - Low-Molecular-Weight Heparin: 6635
        NA-LMWH: 1

Experts

1.	Amirkhosravi, Ali: 1 article (12/2006)
2.	Francis, John L: 1 article (12/2006)
3.	Linhardt, Robert: 1 article (12/2006)
4.	Mousa, Shaker A: 1 article (12/2006)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2006 - "Pre-injection (i.v.) of enoxaparin completely abolished the tumor cell-induced thrombocytopenia, whereas NA-LMWH had no effect. " 12/01/2006 - "Using the B16 melanoma mouse model of metastasis, subcutaneous (s.c.) injection of NA-LMWH or enoxaparin (10 mg/kg), three hours before intravenous (i.v.) injection of metastatic melanoma cells, followed by daily doses for 14 days, reduced lung tumor formation by 70% (P < 0.001). " 12/01/2006 - "In this study, the effect of a non-anticoagulant form of LMWH (NA-LMWH) on experimental lung metastasis and tumor cell-induced platelet aggregation in vivo was compared to the LMWH enoxaparin. "
2.	Neoplasm Metastasis (Metastasis) 12/01/2006 - "Using the B16 melanoma mouse model of metastasis, subcutaneous (s.c.) injection of NA-LMWH or enoxaparin (10 mg/kg), three hours before intravenous (i.v.) injection of metastatic melanoma cells, followed by daily doses for 14 days, reduced lung tumor formation by 70% (P < 0.001). " 12/01/2006 - "In this study, the effect of a non-anticoagulant form of LMWH (NA-LMWH) on experimental lung metastasis and tumor cell-induced platelet aggregation in vivo was compared to the LMWH enoxaparin. "
3.	Thrombocytopenia (Thrombopenia) 12/01/2006 - "Pre-injection (i.v.) of enoxaparin completely abolished the tumor cell-induced thrombocytopenia, whereas NA-LMWH had no effect. "
4.	Experimental Melanoma 12/01/2006 - "Using the B16 melanoma mouse model of metastasis, subcutaneous (s.c.) injection of NA-LMWH or enoxaparin (10 mg/kg), three hours before intravenous (i.v.) injection of metastatic melanoma cells, followed by daily doses for 14 days, reduced lung tumor formation by 70% (P < 0.001). "
5.	Melanoma (Melanoma, Malignant) 12/01/2006 - "Using the B16 melanoma mouse model of metastasis, subcutaneous (s.c.) injection of NA-LMWH or enoxaparin (10 mg/kg), three hours before intravenous (i.v.) injection of metastatic melanoma cells, followed by daily doses for 14 days, reduced lung tumor formation by 70% (P < 0.001). "

Related Drugs and Biologics

1.	Enoxaparin (Lovenox)
2.	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)
3.	Anticoagulants