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4AZA1378

has immunosuppressive activity

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - 4AZA1378: 1

Experts

1.	Boon, Louis: 1 article (01/2007)
2.	Ceuppens, Jan L: 1 article (01/2007)
3.	De Jonghe, Steven: 1 article (01/2007)
4.	Dillissen, Ellen: 1 article (01/2007)
5.	Geboes, Karel: 1 article (01/2007)
6.	Herman, Jean: 1 article (01/2007)
7.	Kasran, Ahmad: 1 article (01/2007)
8.	Kerremans, Luk: 1 article (01/2007)
9.	Lin, Yuan: 1 article (01/2007)
10.	Rutgeerts, Paul: 1 article (01/2007)

Related Diseases

1.

01/01/2007 - "Mice treated with 4AZA1378 had less severe signs of colitis after TNBS rectal administration, with a more rapid weight recovery. "
01/01/2007 - "In conclusion, we identified a pteridine analogue 4AZA1378 with immunosuppressive activity and a strong remission-inducing effect in TNBS colitis, supporting further pre-clinical and clinical development of this novel molecule for treatment of inflammatory diseases."
01/01/2007 - "Immunosuppressive activity of a new pteridine derivative (4AZA1378) alleviates severity of TNBS-induced colitis in mice."

Related Drugs and Biologics

1.	Pteridines

Related Therapies and Procedures

1.	Rectal Administration