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dioscorealide B

an anti-allergic agent isolated from Dioscorea membranacea; structure in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - dioscorealide B: 4

Experts

1.	Itharat, Arunporn: 4 articles (12/2016 - 04/2010)
2.	Graidist, Potchanapond: 3 articles (12/2010 - 04/2010)
3.	Dechsukum, Chavaboon: 2 articles (12/2010 - 12/2010)
4.	Saekoo, Jiraporn: 2 articles (12/2010 - 12/2010)
5.	Ruangnoo, Srisopa: 1 article (12/2016)
6.	Thongdeeying, Pakakrong: 1 article (12/2016)
7.	Umehara, Kaoru: 1 article (12/2016)
8.	Leeanansaksiri, Wilairat: 1 article (12/2010)
9.	Hiransai, Poonsit: 1 article (04/2010)
10.	Purintrapiban, Juntipa: 1 article (04/2010)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 12/01/2010 - "Taken together, the results of this study provide evidence that dioscorealide B possesses an antitumor property against human breast cancer cells and thus provide the molecular basis for the further development of dioscorealide B as a novel chemotherapeutic agent for breast cancer treatment." 12/01/2010 - "To examine the cytotoxic effect and mechanism of Dioscorealide B in human breast carcinoma cells. " 12/01/2010 - "Cytotoxic effect and its mechanism of dioscorealide B from Dioscorea membranacea against breast cancer cells." 12/01/2010 - "Here, we demonstrated that in vitro treatment of dioscorealide B resulted in a cytotoxic effect on MCF-7 human breast cancer cells (IC50 = 2.82 microM). " 12/01/2010 - "Dioscorealide B was isolated from the rhizome of Hua KhaoYen (Dioscorea membranacea).The cytotoxicity of Dioscorealide B was evaluated in two human breast cancer cell lines, MCF-7 and MDA-MB 468 by Sulphorhodamine B (SRB) assay. "
2.	Neoplasms (Cancer) 04/01/2010 - "Dioscorealide B (DB), a naphthofuranoxepin has been purified from an ethanolic extract of the rhizome of Dioscorea membranacea Pierre ex Prain & Burkill which has been used to treat inflammation and cancer in Thai Traditional Medicine. " 12/24/2016 - "Only dioscorealide B (4) might be served as a good anticancer agent for liver cancer and cholangiocarcinoma cancer because it can kill cancer cell but not toxic on normal cell. "
3.	Cholangiocarcinoma 12/24/2016 - "Only dioscorealide B (4) might be served as a good anticancer agent for liver cancer and cholangiocarcinoma cancer because it can kill cancer cell but not toxic on normal cell. "
4.	Liver Neoplasms (Liver Cancer) 12/24/2016 - "Only dioscorealide B (4) might be served as a good anticancer agent for liver cancer and cholangiocarcinoma cancer because it can kill cancer cell but not toxic on normal cell. "
5.	Inflammation (Inflammations) 04/01/2010 - "Dioscorealide B (DB), a naphthofuranoxepin has been purified from an ethanolic extract of the rhizome of Dioscorea membranacea Pierre ex Prain & Burkill which has been used to treat inflammation and cancer in Thai Traditional Medicine. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Antineoplastic Agents (Antineoplastics)
3.	lissamine rhodamine B (sulforhodamine B)

Related Therapies and Procedures

1.	Thai Traditional Medicine