poly(caprolactone-block-ethyleneimine)

structure in first source

Also Known As:

poly(ester amine)

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - poly(caprolactone-block-ethyleneimine): 8
Macromolecular Substances: 97
- Polymers: 13051
  - Polyesters: 921
    - poly(caprolactone-block-ethyleneimine): 8
Biomedical and Dental Materials
- Polymers: 13051
  - Polyesters: 921
    - poly(caprolactone-block-ethyleneimine): 8
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Polyesters: 921
        poly(caprolactone-block-ethyleneimine): 8

Experts

1.	Cho, Chong-Su: 4 articles (05/2013 - 07/2008)
2.	Yang, Yi: 2 articles (01/2018 - 02/2016)
3.	Choung, Pill-Hoon: 2 articles (11/2014 - 05/2013)
4.	Choung, Yun-Hoon: 2 articles (11/2014 - 05/2013)
5.	Chung, Jong Hoon: 2 articles (11/2014 - 05/2013)
6.	Garg, Pankaj: 2 articles (11/2014 - 05/2013)
7.	Pandey, Shambhavi: 2 articles (11/2014 - 05/2013)
8.	Choi, Yun-Jaie: 2 articles (05/2013 - 07/2012)
9.	Cho, Myung-Haing: 2 articles (07/2012 - 07/2008)
10.	Jiang, Hu-Lin: 2 articles (07/2012 - 05/2010)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2013 - "In this study, we demonstrated that the VB6-coupled poly(ester amine) (VBPEA) gene transporter utilizes this uptake mechanism, leading to enhanced vector transport inside the rapidly proliferating cancer cells with relatively high affinity. " 11/01/2014 - "Here we demonstrated that VB6 coupled to poly(ester amine) (VBPEA) enforces a high level of VTC (VB6-transporting membrane carriers)-mediated endocytosis of the complexed SHMT1 siRNA (siSHMT1) to interrupt the thymidylate biosynthesis pathway of cancer cells. " 05/01/2013 - "The efficiency of membrane transport of vitamin B6 coupled to poly(ester amine) gene transporter and transfection in cancer cells." 01/01/2018 - "Tumor-Targeting Anti-MicroRNA-155 Delivery Based on Biodegradable Poly(ester amine) and Hyaluronic Acid Shielding for Lung Cancer Therapy." 02/17/2016 - "First, a tumor-targeted biodegradable folate-poly (ester amine) (FA-PEA) polymer based on low-molecular-weight polyethyleneimine (PEI) was synthesized and characterized, and the application for targeted gene delivery was investigated. "
2.	Wounds and Injuries (Trauma) 01/01/2019 - "Biodegradable amino acid-based poly(ester amine) with tunable immunomodulating properties and their in vitro and in vivo wound healing studies in diabetic rats' wounds."
3.	Lung Neoplasms (Lung Cancer) 05/01/2010 - "Folate conjugated poly(ester amine) for lung cancer therapy." 07/01/2008 - "The use of poly(ester amine) serves as an effective carrier, and aerosol delivery of Akt1 siRNA may be a promising approach for lung cancer treatment and prevention." 01/01/2018 - "Tumor-Targeting Anti-MicroRNA-155 Delivery Based on Biodegradable Poly(ester amine) and Hyaluronic Acid Shielding for Lung Cancer Therapy." 07/01/2008 - "An aerosol of poly(ester amine)/Akt1 siRNA complex was delivered into K-ras(LA1) and urethane-induced lung cancer models through a nose-only inhalation system. "
4.	Carcinogenesis 07/01/2008 - "Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis."
5.	Fibrosis (Cirrhosis) 07/01/2012 - "Kidney-specific peptide-conjugated poly(ester amine) for the treatment of kidney fibrosis."

Related Drugs and Biologics

1.	Amino Acids
2.	Small Interfering RNA (siRNA)
3.	Peptides (Polypeptides)
4.	Folic Acid (Vitamin M)
5.	Vitamin B 6
6.	Hydrogels
7.	Urethane (Ethyl Carbamate)
8.	Polysaccharides (Glycans)
9.	Polyethyleneimine
10.	Hyaluronic Acid (Hyaluronan)

Related Therapies and Procedures

1.	Therapeutics