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RO3244794

structure in first source

Also Known As:

R-3-(4-fluoro-phenyl)-2-(5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino)-propionic acid

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - RO3244794: 2
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - RO3244794: 2
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - RO3244794: 2

Experts

1.	Dercho, Ryan A: 1 article (02/2009)
2.	Di Francesco, Andrea: 1 article (02/2009)
3.	Di Francesco, Luigia: 1 article (02/2009)
4.	Dovizio, Melania: 1 article (02/2009)
5.	Evangelista, Virgilio: 1 article (02/2009)
6.	Pandolfi, Assunta: 1 article (02/2009)
7.	Patrignani, Paola: 1 article (02/2009)
8.	Piccoli, Antonio: 1 article (02/2009)
9.	Salvatore, Tania: 1 article (02/2009)
10.	Seta, Francesca: 1 article (02/2009)

Related Diseases

1.	Inflammation (Inflammations) 02/27/2009 - "The finding that LSS-dependent reduction of TNF-alpha generation and HO-1 induction were abrogated by the selective inhibitor of COX-2 NS-398, the nonselective COX inhibitor aspirin, or the specific prostacyclin receptor (IP) antagonist RO3244794 illuminates the central role played by LSS-induced COX-2-dependent prostacyclin in restraining endothelial inflammation. "
2.	Hyperalgesia 02/01/2006 - "RO1138452 (3-100 mg kg(-1), p.o.) and RO3244794 (0.3-30 mg kg(-1), p.o.) significantly reduced carrageenan-induced mechanical hyperalgesia and edema formation. "
3.	Edema (Dropsy) 02/01/2006 - "RO1138452 (3-100 mg kg(-1), p.o.) and RO3244794 (0.3-30 mg kg(-1), p.o.) significantly reduced carrageenan-induced mechanical hyperalgesia and edema formation. "

Related Drugs and Biologics

1.	Epoprostenol Receptors
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Epoprostenol (Prostacyclin)
4.	Carrageenan
5.	Aspirin (Acetylsalicylic Acid)
6.	(2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline)
7.	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamide