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bromovulone III

is isolated from the soft coral Clavularia viridis, is a cyclopentenone prostanoid; structure in first source

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        bromovulone III: 3
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        bromovulone III: 3

Experts

1.	Guh, Jih-Hwa: 3 articles (08/2006 - 04/2004)
2.	Shen, Ya-Ching: 3 articles (08/2006 - 04/2004)
3.	Chiang, Po-Cheng: 2 articles (08/2006 - 10/2005)
4.	Pan, Shiow-Lin: 2 articles (08/2006 - 10/2005)
5.	Teng, Che-Ming: 2 articles (10/2005 - 04/2004)
6.	Fan, Jia-Rong: 1 article (08/2006)
7.	Huang, Dong-Ming: 1 article (08/2006)
8.	Kung, Fan-Lu: 1 article (08/2006)
9.	Li, Tsai-Kun: 1 article (08/2006)
10.	Chen, Wen-Pin: 1 article (10/2005)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2004 - "Pharmacological study revealed that bromovulone III (7) and chlorovulone II exhibited the most promising cytotoxicity against human prostate (PC-3) and colon (HT29) cancer cells." 08/07/2006 - "In this study, the anti-tumor activity as well as action mechanism of bromovulone III was identified in prostate cancer cells. " 10/01/2005 - "We isolated a marine prostanoid, bromovulone III, from soft coral Clavularia viridis and found that it displayed effective anti-tumor activity in human hepatocellular carcinoma. " 10/01/2005 - "Bromovulone III primarily induced mitochondria-related activation of caspase-9 and -3 in several tumor types, such as prostate cancer PC-3 and acute promyelocytic leukemia HL-60 cells. " 08/07/2006 - "Bromovulone III displayed anti-tumor activity of 30 to 100 times more effective than PGA1, PGA2 and delta12-PGJ2 in PC-3 cells. "
2.	Prostatic Neoplasms (Prostate Cancer) 08/07/2006 - "In this study, the anti-tumor activity as well as action mechanism of bromovulone III was identified in prostate cancer cells. " 10/01/2005 - "Bromovulone III primarily induced mitochondria-related activation of caspase-9 and -3 in several tumor types, such as prostate cancer PC-3 and acute promyelocytic leukemia HL-60 cells. "
3.	Acute Promyelocytic Leukemia 10/01/2005 - "Bromovulone III primarily induced mitochondria-related activation of caspase-9 and -3 in several tumor types, such as prostate cancer PC-3 and acute promyelocytic leukemia HL-60 cells. "
4.	Hepatocellular Carcinoma (Hepatoma) 10/01/2005 - "We isolated a marine prostanoid, bromovulone III, from soft coral Clavularia viridis and found that it displayed effective anti-tumor activity in human hepatocellular carcinoma. "

Related Drugs and Biologics

1.	Caspase 9
2.	Prostaglandins
3.	delta(12)-prostaglandin J(2)
4.	prostaglandin A1 (PGA1)
5.	prostaglandin A2 (PGA2)