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dihydroethidine

a fluorescent dye

Also Known As:

DHE compound

Networked: 16 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Dihydropyridines: 214
      - Dicarbethoxydihydrocollidine: 8
        dihydroethidine: 16

Experts

1.	Chang, Nen-Chung: 2 articles (01/2017 - 05/2016)
2.	Lin, Shinn-Zong: 2 articles (01/2017 - 05/2016)
3.	Spitz, Douglas R: 2 articles (07/2009 - 02/2009)
4.	Kreulen, David L: 2 articles (10/2007 - 01/2006)
5.	Chang, Yeting: 1 article (01/2022)
6.	Ding, Yanchun: 1 article (01/2022)
7.	Hui, Yuanshu: 1 article (01/2022)
8.	Liu, Fengyi: 1 article (01/2022)
9.	Liu, Qinlong: 1 article (01/2022)
10.	Lu, Yi: 1 article (01/2022)

Related Diseases

1.	Ganglion Cysts (Ganglion) 01/01/2006 - "Male Sprague-Dawley rats received intravenous infusions of either the specific ET(B) receptor agonist sarafotoxin 6c (S6c; 5 pmol.kg(-1).min(-1)) or isotonic saline at 0.01 ml/min (control) for 120 min. To measure O2- levels, we removed the inferior mesenteric ganglion immediately after infusion and stained it with dihydroethidine (DHE). " 10/01/2007 - "The reduced nicotinamide-adenine dinucleotide phosphate oxidase activity of ganglion extracts was measured using fluorescence spectrometry of dihydroethidine; the activity in hypertensive dorsal root ganglion was 34% lower than in normotensive DRG. "
2.	Neoplasms (Cancer) 02/15/2009 - "To determine whether oxidative stress mediated by O(2)(-) and hydroperoxides contributed to the differential susceptibility of human epithelial cancer cells to glucose deprivation, the oxidation of DHE (dihydroethidine; for O(2)(-)) and CDCFH(2) [5- (and 6-)carboxy-2',7'-dichlorodihydrofluorescein diacetate; for hydroperoxides] was measured in human colon and breast cancer cells (HT29, HCT116, SW480 and MB231) and compared with that in normal human cells [FHC cells, 33Co cells and HMECs (human mammary epithelial cells)]. " 07/01/2009 - "Treatment of HT29 and HCT116 cancer cells with Antimycin A (Ant A) or rotenone (Rot) increased carboxy-dichlorodihydrofluorescein diacetate (H2DCFDA) and dihydroethidine (DHE) oxidation, caused the accumulation of glutathione disulfide and enhanced 2DG-induced cell killing. "
3.	Ischemia 11/01/2009 - "We evaluated ROS by dihydroethidine (DHE) fluorescence (LV injection, 60 microg/kg, during two episodes of ischemia). " 12/01/1999 - "Cardiomyocytes were exposed to 1 h of simulated ischemia while oxidant generation was assessed by intracellular dihydroethidine (DHE) oxidation. "
4.	Infarction (Infarctions) 01/01/2017 - "Post infarction was associated with increased reactive oxygen species (ROS), as measured by myocardial superoxide levels and dihydroethidine fluorescence staining. " 05/01/2016 - "Post-infarction was associated with increased oxidant stress, as measured by myocardial superoxide, isoprostane, XO activity and dihydroethidine fluorescence staining. "
5.	Hypertension (High Blood Pressure) 01/01/2022 - "We used H&E, Masson, immunofluorescence, dihydroethidine and qPCR to evaluate the effect of Nehesperidin (50 mg/kg/day, 16 days) on pathological hypertension in mice. " 12/01/2019 - "Because hypertension is the most important cerebrovascular risk factor in populations prone to mild brain trauma, we induced mTBI in normotensive and spontaneously hypertensive rats (SHR) and assessed changes in cytoplasmic and mitochondrial superoxide (O2-) production by confocal microscopy in isolated middle cerebral arteries (MCA) 2 weeks after mTBI using dihydroethidine (DHE) and the mitochondria-targeted redox-sensitive fluorescent indicator dye MitoSox. "

Related Drugs and Biologics

1.	Superoxides (Superoxide)
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	Oxidants (Oxidizing Agents)
4.	Fluorescent Dyes (Fluorescent Probes)
5.	2',7'-dichlorodihydrofluorescein diacetate
6.	Isoprostanes
7.	Caspases
8.	Glutathione Disulfide (GSSG)
9.	Annexin A5
10.	Rotenone

Related Therapies and Procedures

1.	Intravenous Infusions