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2,6-di-tert-butyl-4-benzoquinone

structure in first source

Also Known As:

2,6-di-tert-butyl-p-benzoquinone; BHT-quinone

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Cresols: 9
        Butylated Hydroxytoluene: 812
        2,6-di-tert-butyl-4-benzoquinone: 1
- Quinones: 434
  - Benzoquinones: 25
    - 2,6-di-tert-butyl-4-benzoquinone: 1

Related Diseases

1.	Carcinogenesis 06/01/1992 - "Thus, the inhibition of DMBA-induced mammary tumorigenesis by BHT does not appear to be mediated by the oxidative BHT metabolites BHT-BzOH or BHT-quinone. " 06/01/1992 - "However, the decrease in formation of the major mammary adduct derived from the anti-dihydrodiolepoxide of DMBA bound to deoxy-guanosine most closely correlated to the relative abilities of BHT and BHT-quinone to inhibit mammary tumorigenesis. " 06/01/1992 - "In addition, there was a good quantitative correlation between the inhibition of mammary tumorigenesis by BHT and BHT-quinone and their respective abilities to decrease total binding in vivo of DMBA to mammary DNA. " 06/01/1992 - "The present studies were conducted to evaluate the relative effect of the parent chemical BHT and two of its major oxidative metabolites, 2,6-di-tert-butyl-4-hydroxymethylphenol (BHT-BzOH) and 2,6-di-tert-butyl-1,4-benzoquinone (BHT-quinone), on DMBA-induced rat mammary tumorigenesis and on the formation of rat mammary DMBA-DNA adducts in vivo. "
2.	Body Weight (Weight, Body) 06/01/1992 - "The ip administration of either BHT or BHT-quinone at 200 mg/kg body weight for 2 wk before until 1 wk after DMBA administration inhibited the development of mammary tumours as compared with controls. "

Related Drugs and Biologics

1.	DNA Adducts
2.	Butylated Hydroxytoluene (BHT)
3.	2,6-di-tert-butyl-4-hydroxymethylphenol
4.	Guanosine
5.	DNA (Deoxyribonucleic Acid)