pyrachlostrobin (F 500)

Also Known As:

F 500; BAS-500F; F-500; methyl 2-(1-(4-chlorophenyl)pyrazol-3-yloxymethyl)-N-methoxycarbanilate; methyl N-(2-(1-(4-chlorophenyl)-1H-pyrazol-3-yloxymethyl)phenyl)-(N-methoxy)carbamate; pyraclostrobin

Networked: 34 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acrylates: 212
      - Methacrylates: 609
        Strobilurins: 27
        pyrachlostrobin: 34

Experts

1.	Salazar, Gabriela: 2 articles (03/2019 - 03/2016)
2.	Stapleton, Heather M: 2 articles (03/2019 - 01/2018)
3.	Zylka, Mark J: 2 articles (03/2019 - 03/2016)
4.	Fernández-Ortuño, Dolores: 2 articles (11/2016 - 04/2015)
5.	Gao, Yangyang: 1 article (04/2021)
6.	He, Falin: 1 article (04/2021)
7.	He, Lifei: 1 article (04/2021)
8.	Li, Beixing: 1 article (04/2021)
9.	Liu, Feng: 1 article (04/2021)
10.	Mu, Wei: 1 article (04/2021)

Related Diseases

1.	Infections 07/01/2006 - "The effect of pre- and post-infection-period applications of pyraclostrobin (Cabrio EG) on the development of anthracnose fruit rot was characterized in a controlled-climate study and validated in field studies in New York and Florida. " 07/01/2006 - "In three of the four experimental plots, disease control equivalent to or better than the protective spray was achieved when pyraclostrobin was applied up to 24 h after infection for long and short wetting periods. " 07/01/2006 - "We further tested the ability of pyraclostrobin to control anthracnose when applied as a protectant or as an after-infection application in inoculated field plots exposed to a short (8 h) or long (24 h) wetting period in Florida and in New York. " 07/01/2006 - "Post-infection applications of pyraclostrobin provided significant control when applications were made within 3 and often up to 8 h after wetting, but generally were less effective than protective sprays. " 07/01/2006 - "Pre- and Post-Infection Activity of Pyraclostrobin for Control of Anthracnose Fruit Rot of Strawberry Caused by Colletotrichum acutatum."
2.	Mitochondrial Diseases (Mitochondrial Disease) 08/01/2019 - "These results suggested that pyraclostrobin exposure caused cardiotoxicity and neurotoxicity in zebrafish larvae and mitochondrial dysfunction might be the underlying mechanism of pyraclostrobin toxicity." 08/01/2019 - "Mitochondrial dysfunction-based cardiotoxicity and neurotoxicity induced by pyraclostrobin in zebrafish larvae." 11/01/2023 - "The results of fluorescent staining experiments and the expression of cytochrome c, Bcl-2 and Bax demonstrated that pyraclostrobin induced mitochondrial dysfunction, resulting in cell apoptosis. " 10/10/2023 - "We selected low concentrations of boscalid (0.5 µM) and pyraclostrobin (0.25 µM) that did not induce a mitochondrial dysfunction in liver cells when used separately. " 01/01/2018 - "Collectively, these results suggest pyraclostrobin-induced mitochondrial dysfunction inhibits lipid homeostasis, resulting in TG accumulation. "
3.	Breast Neoplasms (Breast Cancer) 01/01/1991 - "A total of 60 patients with advanced breast cancer were treated with a combination of prednimustine (P: 110 mg/m2, days 1-5), mitoxantrone (M: 12 mg/m2, day 1) and 5-fluorouracil (F: 500 mg/m2, day 1) (PMF). " 03/01/2003 - "Locally advanced breast cancer patients were randomly assigned onto a study comparing cyclophosphamide (C; 75 mg/m(2) orally days 1 to 14), epirubicin (E; 60 mg/m(2) intravenously [IV] days 1, 8), and fluorouracil (F; 500 mg/m(2) IV days 1, 8) six cycles every 28 days versus E (120 mg/m(2) IV day 1), C (830 mg/m(2) IV day 1), and granulocyte colony-stimulating factor (filgrastim; 5 micro g/kg/d subcutaneously days 2 to 13) six cycles every 14 days. "
4.	Mycoses (Diseases, Fungus) 12/02/2023 - "Pyraclostrobin was widely used to control the fungal diseases of nectar and pollen plants, though it was not friend to honey bees and other pollinators. " 12/01/2022 - "Pyraclostrobin (PYR), a strobilurin fungicide, has been widely used to control fungal diseases, posing potential risk to aquatic organisms. " 04/01/2021 - "Pyraclostrobin (PYR), a fungicide of the strobilurin class, is used to control many different kinds of fungal diseases in greenhouses and on agricultural fields. " 01/01/2023 - "The strobilurin fungicide pyraclostrobin is widely used to prevent and control the fungal diseases of various nectar and pollen plants. "
5.	Branchiootic syndrome 11/01/2016 - "Resistance to boscalid, fenhexamid, iprodione, and pyraclostrobin was found to be caused by amino acid substitutions on target proteins, including H272R/Y in SdhB, F412I/S/V in Erg27, I365 N/S in Bos1, and G143A in Cytb, respectively. " 03/09/2021 - "Resistance conferring mutations were found in a selection of isolates characterized as resistant to thiophanate-methyl, iprodione, pyraclostrobin, fenhexamid, and boscalid including E198A in β-tubulin; I365N/S, Q369P, and N373S in bos1; G143A in cytb; P238S, N369D, and F412I/S in erg27; and P225F and H272R/Y in sdhB, respectively. " 04/01/2015 - "Resistance to thiophanate-methyl, iprodione, boscalid, pyraclostrobin, and fenhexamid was based on target gene mutations that conferred E198A and F200Y in β-tubulin, I365N/S in Bos1, H272R/Y in SdhB, G143A in Cytb, and T63I and F412S in Erg27. "

Related Drugs and Biologics

1.	Strobilurins
2.	pyrachlostrobin (F 500)
3.	azoxystrobin
4.	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)
5.	Messenger RNA (mRNA)
6.	Fluorouracil (Carac)
7.	Granulocyte Colony-Stimulating Factor (G-CSF)
8.	Epirubicin (Ellence)
9.	Cyclophosphamide (Cytoxan)
10.	Filgrastim (Neupogen)