fumarate N- ((4- (4,5- dihydro- 1H- imidazol- 2- yl)phenyl)methyl)- 2- (2- (((4- methoxy- 2,6- dimethylphenyl) sulfonyl)methylamino)ethoxy)- N- methylacetamide

structure in first source

Also Known As:

N-((4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)methyl)-2-(2-(((4-methoxy-2,6-dimethylphenyl) sulfonyl)methylamino)ethoxy)-N-methylacetamide, fumarate; LF22-0542

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Acrylamides: 12
    - fumarate N-((4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)methyl)-2-(2-(((4-methoxy-2,6-dimethylphenyl) sulfonyl)methylamino)ethoxy)-N-methylacetamide: 4
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acrylates: 212
      - Acrylamides: 12
        fumarate N-((4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)methyl)-2-(2-(((4-methoxy-2,6-dimethylphenyl) sulfonyl)methylamino)ethoxy)-N-methylacetamide: 4
    - Dicarboxylic Acids: 108
      - Fumarates: 813
        fumarate N-((4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)methyl)-2-(2-(((4-methoxy-2,6-dimethylphenyl) sulfonyl)methylamino)ethoxy)-N-methylacetamide: 4

Experts

1.	Couture, R: 2 articles (02/2008 - 12/2007)
2.	Dias, J P: 2 articles (02/2008 - 12/2007)
3.	Ongali, B: 2 articles (02/2008 - 12/2007)
4.	Couture, Réjean: 1 article (01/2012)
5.	Dotigny, Florence: 1 article (01/2012)
6.	Pouliot, Mylène: 1 article (01/2012)
7.	Sénécal, Jacques: 1 article (01/2012)
8.	Talbot, Sébastien: 1 article (01/2012)
9.	Vaucher, Elvire: 1 article (01/2012)
10.	Neugebauer, W: 1 article (02/2008)

Related Diseases

1.	Hyperalgesia 02/01/2008 - "At day 21 after sciatic nerve ligation, thermal hyperalgesia was blocked by LF22-0542 (10 mg/kg, s.c.) and LF16-0687 (3 mg/kg, s.c.), yet both antagonists had no effect on tactile and cold allodynia. " 12/01/2007 - "LF22-0542 reduced tactile and cold allodynia (3h) and reversed arterial hypertension (3-48h) in glucose-fed rats. "
2.	Pain (Aches) 07/01/2006 - "LF22-0542 alleviated thermal hypersensitivity in both acute (carrageenan) and persistent inflammatory (complete Freund's adjuvant) pain models in rats. "
3.	Neuralgia (Stump Neuralgia) 02/01/2008 - "Hence LF22-0542 and LF16-0687 present therapeutic potential for the treatment of some aspects of neuropathic pain."
4.	Inflammation (Inflammations) 01/01/2012 - "Ocular application of the kinin B1 receptor antagonist LF22-0542 inhibits retinal inflammation and oxidative stress in streptozotocin-diabetic rats."
5.	Hypertension (High Blood Pressure) 12/01/2007 - "LF22-0542 reduced tactile and cold allodynia (3h) and reversed arterial hypertension (3-48h) in glucose-fed rats. "

Related Drugs and Biologics

1.	Streptozocin (Streptozotocin)
2.	Retinaldehyde (Retinal)
3.	Kinins
4.	Glucose (Dextrose)
5.	Freund's Adjuvant
6.	Carrageenan
7.	LF 16-0687

Related Therapies and Procedures

1.	Ligation