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1,7- dimethyl- 1,4,7,10- tetraazacyclododecane

promotes DNA hydrolysis; structure in first source

Also Known As:

DMTACD cpd; maltonis

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1,7-dimethyl-1,4,7,10-tetraazacyclododecane: 1

Experts

1.	Amatori, Stefano: 1 article (02/2014)
2.	Balducci, Mauro: 1 article (02/2014)
3.	Fanelli, Mirco: 1 article (02/2014)
4.	Fusi, Vieri: 1 article (02/2014)
5.	Giorgi, Luca: 1 article (02/2014)
6.	Guerzoni, Clara: 1 article (02/2014)
7.	Landuzzi, Lorena: 1 article (02/2014)
8.	Lollini, Pier-Luigi: 1 article (02/2014)
9.	Magnani, Mauro: 1 article (02/2014)
10.	Manara, Maria Cristina: 1 article (02/2014)

Related Diseases

1.

Sarcoma (Soft Tissue Sarcoma)

02/27/2014 - "An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas."
02/27/2014 - "Maltonis, a soluble maltol-derived synthetic molecule, was able to alter the DNA structure, inhibit proliferation and induce apoptotic cell death in paediatric sarcoma cells, either sensitive or resistant to some conventional chemotherapeutic drugs, such as doxorubicin and cisplatin. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	DNA (Deoxyribonucleic Acid)
3.	Cisplatin (Platino)
4.	maltol