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amyrone

from Sedum sarmentosum

Also Known As:

delta-amyrone

Networked: 4 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - amyrone: 4

Experts

1.	Li, Huani: 3 articles (10/2015 - 07/2014)
2.	Li, Weifeng: 3 articles (10/2015 - 07/2014)
3.	Mu, Qingli: 3 articles (10/2015 - 07/2014)
4.	Niu, Xiaofeng: 3 articles (10/2015 - 07/2014)
5.	Yao, Huan: 3 articles (10/2015 - 07/2014)
6.	Wang, Yu: 2 articles (10/2015 - 06/2015)
7.	Zhang, Hailin: 2 articles (10/2015 - 06/2015)
8.	Boleti, Ana Paula de A: 1 article (01/2015)
9.	Lima, Emerson S: 1 article (01/2015)
10.	Lourenço, Geane A: 1 article (01/2015)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2015 - "This study may provide the basis for future investigations on the therapeutic role of α,β-amyrone in treating inflammation. " 10/05/2015 - "δ-Amyrone (13(18)-Oleanen-3-one), which is an active constituent extracted and separated from Sedum lineare Thunb., has been found to possess a potent anti-inflammatory effect in different inflammation model animals. "
2.	Stomach Ulcer (Gastric Ulcer) 06/01/2015 - "The purpose of this study is to examine the protective effect of δ-amyrone on ethanol-induced gastric ulcer in mice. " 06/01/2015 - "Protective effect of δ-amyrone against ethanol-induced gastric ulcer in mice." 06/01/2015 - "These results suggested that δ-amyrone exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO. Thus, δ-amyrone shows promise as a therapeutic agent in experimental gastric ulcer."
3.	Shock 10/05/2015 - "The aim of this study is to evaluate the effect of δ-Amyrone on LPS-induced inflammatory cytokines and the protective effect on endotoxic shock mice. " 10/05/2015 - "These results suggest that the protective activity of δ-amyrone on LPS-induced endotoxic shock is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression." 10/05/2015 - "δ-Amyrone inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice."
4.	Edema (Dropsy) 01/01/2015 - "α,β-Amyrone inhibited the expression of COX-2 and also inhibited the formation of paw or ear edema in rats and mice, having a quick and immediate effect. " 07/01/2014 - "Pretreatment with δ-Amyrone (i.p.) inhibited the ear edema in xylene-induced mouse ear edema. "
5.	Ulcer 06/01/2015 - "The gastric lesions were significantly attenuated by δ-amyrone (4 and 8 mg/kg) as compared to the ulcer control group. "

Related Drugs and Biologics

1.	Cytokines
2.	Ethanol (Ethyl Alcohol)
3.	Interleukin-6 (Interleukin 6)
4.	Nitric Oxide (Nitrogen Monoxide)
5.	Acetic Acid (Vinegar)
6.	Dinoprostone (PGE2)
7.	Xylenes (Xylene)
8.	Lipopolysaccharides
9.	Enzymes