First Step

01/01/2006 - "Since a cancer is cured when most, if not all, cancer cells are killed, the preliminary evaluation of the spatial diffusion of any injected gene construct should be carried out as a first step in any cancer type."
08/01/2014 - "Our understanding of surgery of the primary tumor in LN-positive PCa needs a conceptual change from a palliative option to the first step in a multimodal approach with a significant improvement of long-term survival and cure in selected patients."
01/01/2009 - "This experience probably represents the first step toward an effective treatment of malignant vascular tumors in infancy."
12/01/2013 - "CEUS can be used as the first step in the diagnosis of liver lesions, but MRI remains the gold standard diagnostic method for liver tumors."
03/01/2016 - "Recognizing the Limitations of Cancer Overdiagnosis Studies: A First Step Towards Overcoming Them."

10/01/1979 - "Even though the malignancy cannot be eradicated, an important first step in pain control is the diagnostic identification of the source of pain because it is preferable to treat the pain specifically rather than symptomatically. "
05/01/2010 - "Because 1 in 3 opioid-maintained pain patients may be affected, it is essential that healthcare providers learn more about this subpopulation as a first step toward improved detection, brief intervention, referral, and general management. "
10/01/1993 - "We are convinced that the HET-CAM-test can be a very useful first step in distinguishing between irritative and non irritative substances and in protecting animals from pain, even in the event that the results of both tests do not clearly correspond to each other. "
10/01/2014 - "Compared with preoperative measures, pain (first step in the morning, during walking, at the end of the day) and function (descending the stairs, ascending the stairs, and ambulating up to 4 blocks) improved postoperatively at 6 and 12 months (P ≤ .001). "
01/01/2006 - "Participants treated with low-Dye taping reported a small improvement in 'first-step' pain after one week of treatment compared to those who did not receive taping. "

03/01/2003 - "Spontaneous resolution of hepatitis C virus (HCV) infection is a relatively infrequent event, and these individuals provide a unique opportunity to characterize correlates of protective immunity as an important first step in the development of vaccine candidates. "
10/19/2012 - "Collectively, our results represent a successful first step toward the development of a safe and effective vaccine against CVA16 infection."
09/01/2014 - "The objective of this study was to investigate if and how cow factors and intramammary infection (IMI) are associated with 4 different udder-health indicators in dairy cows as a first step in investigating whether the diagnostic performance of these indicators can be improved. "
07/17/2011 - "These findings represent a first step towards a remission of primate lentiviral infections."
05/01/2015 - "Experimental oral infection with FV3 in captive-raised adult wood frogs, Rana sylvatica Lithobates sylvaticus, was performed as the first step in establishing a native North American animal model of ranaviral disease to study pathogenesis and host response. "

05/01/2000 - "In conclusion, we find evidence to suggest that a greater initial weight loss as the first step of a weight management programme may result in improved sustained weight maintenance."
10/01/2011 - "The first step in the management of low HDL-C is lifestyle interventions: weight loss, physical activity and smoking cessation are effective in increasing HDL-C. "
01/01/2013 - "This study presents the first step in examining the role that novelty and user control may play in two different weight-loss electronic media, as well as differences in knowledge acquisition. "
02/01/2011 - "As a first step in this direction, this study examined the experiences, concerns, and beliefs regarding diet, weight and weight loss of Mexican-American immigrant women. "
02/01/2015 - "In obese HG men, lifestyle modifications and, in particular, weight loss should be the first step. "

11/01/2013 - "A systematic evaluation and physical examination of the trauma victim remain the gold standard and the first step toward effective care. "
11/01/1998 - "The quantification of risk, as we have reported here, is the first step towards addressing the causes of musculoskeletal breakdown and should help in applying a reasoned approach to intervention measures that may be effective in reducing racing injuries."
06/01/2015 - "This study supports WHO recommendations to utilize the strengths of a developing nation-population-as the first step in establishing an organized trauma triage system."
01/01/2015 - "The results of this study will be the first step for clinicians in VA and military settings to generate evidence-based treatment and care approaches to these injuries. "
09/01/2014 - "The objective of this study was to gain an understanding of patterns of pediatric trauma transfer to all pediatric trauma centers within the region as a first step in assessing the efficacy and efficiency of trauma triage. "