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spiro(imidazo- (1,2- a)pyridine- 3,2- indan)- 2(3H)- one

Subscribe to New Research on spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one

structure in first source

Also Known As:

ST 101; ST-101; ST101 cpd; ZSET 1446; ZSET1446

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Cyclic Hydrocarbons: 3
    - Aromatic Hydrocarbons: 132
      - Aromatic Polycyclic Hydrocarbons: 831
        Indenes: 2
        Indans: 4
        spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one: 3
        Spiro Compounds: 1
        spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one: 3
Polycyclic Compounds: 56
- Aromatic Polycyclic Hydrocarbons: 831
  - Indenes: 2
    - Indans: 4
      - spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one: 3
  - Spiro Compounds: 1
    - spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one: 3

Experts

1.	Yamaguchi, Yoshimasa: 2 articles (07/2008 - 06/2006)
2.	Hino, Masataka: 1 article (07/2008)
3.	Shioda, Norifumi: 1 article (07/2008)
4.	Yamamoto, Yui: 1 article (07/2008)
5.	Han, Feng: 1 article (07/2008)
6.	Raie, Alisa Y Ali: 1 article (07/2008)
7.	Fukunaga, Kohji: 1 article (07/2008)
8.	Moriguchi, Shigeki: 1 article (07/2008)
9.	Nagai, Taku: 1 article (02/2007)
10.	Takuma, Kazuhiro: 1 article (02/2007)

Related Diseases

1.	Memory Disorders (Memory Loss) 07/01/2008 - "Here, we found that chronic oral administration of spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) (0.1-1 mg/kg/day), a novel cognitive enhancer, significantly improved memory deficits as assessed by Y-maze and novel object recognition tasks in OBX mice. "
2.	Alzheimer Disease (Alzheimer's Disease) 06/01/2006 - "These results suggest that ZSET1446 may be a potential candidate for development as a therapeutic agent to manage cognitive impairment associated with conditions such as Alzheimer's disease." 02/01/2007 - "ZSET1446 would be a potential candidate for further preclinical study aimed at the treatment of cognitive deficits in Alzheimer's disease and schizophrenia, as well as METH psychosis."
3.	Schizophrenia (Dementia Praecox) 02/01/2007 - "ZSET1446 would be a potential candidate for further preclinical study aimed at the treatment of cognitive deficits in Alzheimer's disease and schizophrenia, as well as METH psychosis."

Related Drugs and Biologics

1.	indan
2.	pyridine

Related Therapies and Procedures

1.	Oral Administration