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3beta,6beta,16beta- trihidroxilup- 20(29)- ene

from the flowers of Combretum leprosum; structure in first source

Also Known As:

3beta 6beta,16beta-trihydroxylup-20(29)-ene; TH-terpene

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - 3beta,6beta,16beta-trihidroxilup-20(29)-ene: 1

Experts

1.	Facundo, Valdir A: 1 article (01/2006)
2.	Marques, Maria Consuelo A: 1 article (01/2006)
3.	Pietrovski, Evelise F: 1 article (01/2006)
4.	Rios, Katiuscia: 1 article (01/2006)
5.	Rosa, Kelson A: 1 article (01/2006)
6.	Santos, Adair R S: 1 article (01/2006)

Related Diseases

1.

01/01/2006 - "The present study examined the antinociceptive effects of the ethanolic extract (EE) and of the triterpene 3beta,6beta,16beta-trihidroxilup-20(29)-ene obtained from the flowers of Combretum leprosum in chemical and thermal behavioural models of pain in mice. "
01/01/2006 - "Furthermore, the triterpene 3beta,6beta,16beta-trihidroxilup-20(29)-ene (1-30 mg/kg), given p.o., 1 h prior to testing, also produced dose-related inhibition of glutamate-induced pain, with a mean ID50 value of 5.6 mg/kg. When assessed in a thermal model of pain, the EE (10-300 mg/kg, p.o.) and fentanyl (100 microg/kg, s.c.) caused a significant and marked increase in the latency response on the hot-plate test (50 degrees C). "

Related Drugs and Biologics

1.	Triterpenes
2.	Glutamic Acid (Glutamate)
3.	Fentanyl (Sublimaze)