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pimavanserin

A 5-HT(2A) inverse agonist; ACP-103 is the dihydroxybutanedioate (2:1) salt. It is used to treat hallucinations and delusions associated with PARKINSON DISEASE; structure in first source.
Also Known As:
ACP 103; ACP-103; ACP103; N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide; Nuplazid; bis(1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-(4-(2-methylpropoxy)benzyl)urea) (2R,3R)-2,3-dihydroxybutanedioate; pimavanserin tartrate; urea, n-((4-fluorophenyl)methyl)-n-(1-methyl-4-piperidinyl)-n'-((4-(2-methylpropoxy)phenyl)methyl)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
Networked: 202 relevant articles (49 outcomes, 42 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ballard, Clive: 11 articles (01/2022 - 02/2014)
2. Stankovic, Srdjan: 11 articles (01/2022 - 01/2018)
3. Friedman, Joseph H: 8 articles (01/2022 - 03/2010)
4. Coate, Bruce: 8 articles (01/2021 - 10/2015)
5. Norton, James C: 7 articles (03/2022 - 04/2017)
6. Aarsland, Dag: 6 articles (01/2022 - 01/2017)
7. Isaacson, Stuart: 6 articles (01/2020 - 02/2014)
8. Burstein, Ethan S: 5 articles (01/2022 - 10/2014)
9. Williams, Hilde: 5 articles (10/2020 - 03/2010)
10. Hermanowicz, Neal: 5 articles (07/2019 - 01/2016)

Related Diseases

1. Psychotic Disorders (Schizoaffective Disorder)
2. Parkinson Disease (Parkinson's Disease)
3. Hallucinations (Hallucination)
4. Alzheimer Disease (Alzheimer's Disease)
5. Dementia (Dementias)

Related Drugs and Biologics

1. Antipsychotic Agents (Antipsychotics)
2. Clozapine (Clozaril)
3. 5-HT2A Serotonin Receptor (5 HT2A Receptor)
4. Serotonin (5 Hydroxytryptamine)
5. pimavanserin
6. Cholinesterase Inhibitors (Anticholinesterases)
7. Levodopa (L Dopa)
8. Antidepressive Agents (Antidepressants)
9. Lithium
10. Escitalopram

Related Therapies and Procedures

1. Therapeutics
2. Deep Brain Stimulation
3. Secondary Prevention
4. Long-Term Care
5. Drug Therapy (Chemotherapy)