HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

kobophenol A

structure in first source

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        kobophenol A: 4

Experts

1.	Kwak, Jong Hwan: 2 articles (01/2014 - 04/2007)
2.	Lee, Sung Ryul: 2 articles (01/2014 - 04/2007)
3.	Pyo, Suhkneung: 2 articles (11/2013 - 04/2007)
4.	Acevedo, Orlando: 1 article (02/2021)
5.	Badavath, Vishnu Nayak: 1 article (02/2021)
6.	Blum, Galia: 1 article (02/2021)
7.	De Jonghe, Steven: 1 article (02/2021)
8.	Gangadevi, Suresh: 1 article (02/2021)
9.	Jochmans, Dirk: 1 article (02/2021)
10.	Leyssen, Pieter: 1 article (02/2021)

Related Diseases

1.	Osteoporosis 11/01/2013 - "Taken together, the results of this study reveal that kobophenol A has proliferative effects and enhances ALP activity in osteoblast cells and these findings provide insights into the development of a therapeutic approach of kobophenol A in the prevention of osteoporosis and other bone disorders."
2.	COVID-19 02/25/2021 - "In summary, Kobophenol A, identified through docking studies, is the first compound that inhibits SARS-CoV-2 binding to cells through blocking S1-RBD to the host ACE2 receptor and thus may serve as a good lead compound against COVID-19." 02/25/2021 - "Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19."
3.	Cardiotoxicity 01/01/2014 - "For finding a natural compound that suppressing SNP-induced cardiac toxicity, we tested the protective potential of kobophenol A (Kob A), purified from the root of Caragana sinica, against the toxic effects of SNP. "
4.	Virus Diseases (Viral Diseases) 02/25/2021 - "Kobophenol A was then found to block the interaction between the ACE2 receptor and S1-RBD in vitro with an IC50 of 1.81 ± 0.04 μM and inhibit SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. "
5.	Neuroblastoma 04/01/2007 - "Neuroprotective effects of kobophenol A against the withdrawal of tropic support, nitrosative stress, and mitochondrial damage in SH-SY5Y neuroblastoma cells."

Related Drugs and Biologics

1.	Neuroprotective Agents