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TGN-1412 (TGN1412)

humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer but withdrawn due to severe toxicity
Also Known As:
TGN1412; TAB-08; TAB08; TGN 1412; TGN-1412 monoclonal antibody; monoclonal antibody TGN1412; theralizumab
Networked: 47 relevant articles (3 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hünig, Thomas: 7 articles (07/2016 - 01/2009)
2. Stebbings, Richard: 7 articles (06/2015 - 09/2007)
3. Eastwood, David: 5 articles (06/2015 - 09/2007)
4. Thorpe, Susan J: 5 articles (06/2015 - 09/2007)
5. Poole, Stephen: 5 articles (08/2013 - 09/2007)
6. Thorpe, Robin: 5 articles (08/2013 - 09/2007)
7. Römer, Paula S: 4 articles (07/2016 - 12/2011)
8. Stebbings, R: 4 articles (09/2015 - 10/2010)
9. Ball, Christina: 4 articles (06/2015 - 07/2011)
10. Findlay, Lucy: 4 articles (08/2013 - 09/2007)

Related Diseases

1. Cytokine Release Syndrome
2. Rheumatoid Arthritis
3. B-Cell Leukemia (Leukemia, B Cell)
4. Autoimmune Diseases (Autoimmune Disease)
5. Acute Pain

Related Drugs and Biologics

1. TGN-1412 (TGN1412)
2. Antibodies
3. Monoclonal Antibodies
4. Cytokines
5. Interleukin-2 (IL2)
6. rofecoxib (Vioxx)
7. Alemtuzumab (Campath)
8. Muromonab-CD3 (Muromonab CD3)
9. Integrins
10. Interleukin-6 (Interleukin 6)

Related Therapies and Procedures

1. Drug Tapering
2. Therapeutics