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rat Tpsab1 protein

RefSeq NM_019322

Also Known As:

Tpsab1 protein, rat; Mcpt7 protein, rat; TPSB1 protein, rat; mast cell protease 7, rat; rMCP-7 protein, rat; tryptase alpha-beta 1; tryptase beta 1, rat

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Tryptases: 2102
        rat Tpsab1 protein: 3
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Tryptases: 2102
        rat Tpsab1 protein: 3

Experts

1.	Harsulkar, Abhay: 1 article (01/2022)
2.	Koks, Sulev: 1 article (01/2022)
3.	Kulkarni, Priya: 1 article (01/2022)
4.	Märtson, Aare: 1 article (01/2022)
5.	Märtson, Anne-Grete: 1 article (01/2022)
6.	Suutre, Siim: 1 article (01/2022)
7.	Arkwright, Peter D: 1 article (11/2020)
8.	Beaman, Glenda: 1 article (11/2020)
9.	Bonin, Hope: 1 article (11/2020)
10.	Briggs, Tracy A: 1 article (11/2020)

Related Diseases

1.	Osteophyte 01/04/2022 - "(In IHC, anti-tryptase alpha/beta-1 and anti- FC epsilon RI-stained active mast cells were seen populated in cartilage, subchondral bone, and trabecular bone.) Based on these outcomes and previous learnings, the authors claim a possibility of mast cells invasion into osteophytes is mediated by SF and present in vitro cell differentiation assay results, wherein ThP1 and HSCs showed differentiation into HLA-DR+/CD206+ and FCERI+ phenotype, respectively, after exposing them to medium containing 10% SF for 9 days. " 01/04/2022 - "Presence of mast cells was further confirmed by immunohistochemistry, performed on the sections of the osteophytes using anti-tryptase alpha/beta-1 and anti-FC epsilon RI antibodies and the related key up-regulated genes were validated by qRT-PCR. "
2.	Chronic Renal Insufficiency 01/01/2023 - "The discovery of hereditary α-tryptasemia (HαT)-a genetic trait caused by an increased copy number of the Tryptase Alpha/Beta 1 (TPSAB1) gene-, first described in 2016, is now known to underlie the majority of cases of elevated BST outside of cMCD and chronic kidney disease. "
3.	Hereditary alpha-tryptasemia syndrome 11/01/2020 - "Hereditary alpha-tryptasemia (HAT) is a genetic trait caused by an increased alpha-tryptase tryptase alpha/beta 1 gene copy number. "

Related Drugs and Biologics

1.	Tryptases (Tryptase)
2.	IgE Receptors (Fc epsilon RI)
3.	HLA-DR Antigens (HLA-DR)
4.	Antibodies