1-(2-(2-thienyl)-2-adamantyl) morpholine

03/01/2010 - "In this study, we developed a qualitative GC-MS method to measure elimination of TCP and TAMORF through rat urine in order to learn more about the mechanisms through which TCP protects an organism from OP poisoning and to determine the duration of this protective effect. "
01/01/2006 - "Treatment with Tamorf seems to be a good alternative for current pretreatment in soman poisoning. "
01/01/2006 - "Evaluation of antidotal effects of adamantyl derivative Tamorf in soman poisoning."
01/01/2006 - "Tamorf administered 5 min before poisoning stopped soman-induced seizures, was successful against sub-lethal doses of soman and protected AChE activity in the brain (P = 0.0014, P = 0.0019), and in plasma (P = 0.0464, P = 0.0405). "
01/01/2006 - "Compared with Tamorf, physostigmine was slightly effective in the elimination of soman-induced poisoning in rats. "

12/01/2006 - "Since TAMORF was found to significantly inhibit cell growth and proliferation in vitro, it is reasonably to consider it as a source molecule promising for further modifications and development of more potent substances with antitumor properties rather then radioprotector or antidote in organophosphorus poisoning."

01/01/2006 - "Tamorf administered 5 min before poisoning stopped soman-induced seizures, was successful against sub-lethal doses of soman and protected AChE activity in the brain (P = 0.0014, P = 0.0019), and in plasma (P = 0.0464, P = 0.0405). "

04/01/2002 - "These compounds with potential activity at the N-methyl- D-aspartate and muscarinic receptors showed low acute toxicity, having LD50 values varying from 106.00 mg/kg (TCP) to >504.00 mg/kg body weight (TAMORF). "