HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2-acetylfuranonaphthoquinone

has antineoplastic activity; structure in first source

Also Known As:

2-acetyl furanonaphthoquinone; FNQ cpd

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Rieber, Manuel: 2 articles (08/2008 - 03/2005)
2.	Rieber, Mary Strasberg: 2 articles (08/2008 - 03/2005)
3.	Medina, Jose D: 1 article (03/2005)
4.	Solórzano, Leobaldo: 1 article (03/2005)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2005 - "In this study, we investigated whether glucose deprivation or substitution by fructose regulates tumor cell apoptosis induced by 2-acetyl furanonaphthoquinone (FNQ). " 08/01/2008 - "2-acetyl furanonaphthoquinone (FNQ) is a naturally occurring drug with enhanced toxicity versus glucose-starved tumor cells, which frequently show topoisomerase II drug resistance. "
2.	Melanoma (Melanoma, Malignant) 03/01/2005 - "Decreased glycolytic metabolism accelerates apoptosis in response to 2-acetyl furanonaphthoquinone in K1735 melanoma irrespective of bcl-2 overexpression." 08/01/2008 - "Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase mediate melanoma apoptosis induced by 2-acetyl furanonaphthoquinone: roles of Bcl-2 and p53."

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Fructose
3.	JNK Mitogen-Activated Protein Kinases
4.	Type II DNA Topoisomerases (Topoisomerase II)