pegylated erythropoietin

rhEPO conjugated with a polyethylene glycol

Also Known As:

Ro 50-3821

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Colony-Stimulating Factors: 1599
      - Erythropoietin: 12227
        pegylated erythropoietin: 5
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1599
        Erythropoietin: 12227
        pegylated erythropoietin: 5
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Hematopoietic Cell Growth Factors: 13
      - Colony-Stimulating Factors: 1599
        Erythropoietin: 12227
        pegylated erythropoietin: 5
Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - Ethylene Glycols: 8
      - Polyethylene Glycols: 3865
        pegylated erythropoietin: 5
Macromolecular Substances: 97
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - pegylated erythropoietin: 5
Biomedical and Dental Materials
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - pegylated erythropoietin: 5
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Polyethylene Glycols: 3865
        pegylated erythropoietin: 5

Experts

1.	Jain, Deepak: 1 article (10/2021)
2.	Nand, Nitya: 1 article (10/2021)
3.	Nandan, Raghu: 1 article (10/2021)
4.	Hong, Jin Tae: 1 article (03/2020)
5.	Hwang, Chul Ju: 1 article (03/2020)
6.	Im, Jun Hyung: 1 article (03/2020)
7.	Lee, Kyung Sun: 1 article (03/2020)
8.	Yeo, In Jun: 1 article (03/2020)
9.	Schmid, Holger: 1 article (05/2013)
10.	Geyer, Hans: 1 article (07/2012)

Related Diseases

1.	Anemia 05/01/2013 - "Peginesatide, recently approved in the US for once-monthly dosing in adult patients on dialysis, is a promising novel PEGylated erythropoietin-mimetic peptide for the treatment of renal disease-induced anemia. " 10/01/2021 - "This study was carried out to evaluate the effect of pegylated erythropoietin and to compare its effects with the effects of darbepoetin alfa on anemia of chronic kidney patients on maintenance hemodialysis having erythropoietin hyporesponsiveness. " 10/01/2021 - "Comparative Effects of Pegylated Erythropoietin and Darbepoetin Alfa on Erythropoietin Hyporesponsive Anemia of Patients with Chronic Kidney Disease on Maintenance Hemodialysis."
2.	Renal Insufficiency (Renal Failure) 01/01/2006 - "Sprague-Dawley rats with surgically induced renal insufficiency received Ro 50-3821 or MIX subcutaneously (s.c.) over 4-12 weeks compared to rhEPO and NaCl. " 07/01/2012 - "As target analyte, peginesatide (Omontys, Hematide), a recently approved pegylated erythropoietin-mimetic peptide of approximately 45 kDa, tested for the treatment of anaemia in patients with renal failure, was chosen, which has been prohibited in elite sports due to its assumed endurance enhancing effects. "
3.	Chronic Renal Insufficiency 10/01/2021 - "Comparative Effects of Pegylated Erythropoietin and Darbepoetin Alfa on Erythropoietin Hyporesponsive Anemia of Patients with Chronic Kidney Disease on Maintenance Hemodialysis."
4.	Stroke (Strokes) 03/01/2020 - "PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation."
5.	Brain Injuries (Brain Injury) 03/01/2020 - "PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation."

Related Drugs and Biologics

1.	Erythropoietin
2.	Darbepoetin alfa (Aranesp)
3.	Peptides (Polypeptides)
4.	peginesatide
5.	Iron
6.	hematide

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)