CC-5079

a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Muller, George W: 2 articles (11/2010 - 01/2006)
2.	Payvandi, Faribourz: 2 articles (11/2010 - 01/2006)
3.	Schafer, Peter H: 2 articles (11/2010 - 01/2006)
4.	Stirling, David I: 2 articles (11/2010 - 01/2006)
5.	He, Mei: 1 article (11/2010)
6.	Libutti, Steven K: 1 article (11/2010)
7.	Miller, Walter J: 1 article (11/2010)
8.	O'Connor, Sarah A: 1 article (11/2010)
9.	Vu, Huan N: 1 article (11/2010)
10.	Bartlett, J Blake: 1 article (01/2006)

1.	Neoplasms (Cancer) 11/01/2010 - "Third, CC-5079 antitumor effect was determined in treatment of C57BL/6 mice with MC38 tumors. " 01/15/2006 - "CC-5079 inhibits proliferation of cancer cell lines from various organs and tissues at nanomolar concentrations. " 01/15/2006 - "We have found that the synthetic compound CC-5079 potently inhibits cancer cell growth in vitro and in vivo by a novel combination of molecular mechanisms. " 01/15/2006 - "Moreover, in a mouse xenograft model using HCT-116 human colorectal tumor cells, CC-5079 significantly inhibits tumor growth in vivo. " 01/15/2006 - "Our data indicate that CC-5079 inhibits cancer cell growth with a mechanism of action similar to that of other tubulin inhibitors. "
2.	Colorectal Neoplasms (Colorectal Cancer) 01/15/2006 - "Moreover, in a mouse xenograft model using HCT-116 human colorectal tumor cells, CC-5079 significantly inhibits tumor growth in vivo. "