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prion protein (90-231)

Also Known As:

Prp(90-231)

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Prions: 4777
    - prion protein (90-231): 3
- Peptides: 82426
  - Peptide Fragments: 373
    - prion protein (90-231): 3

Experts

1.	Alonso, Jana: 1 article (06/2011)
2.	Gong, Binbin: 1 article (06/2011)
3.	Liu, Zengshan: 1 article (06/2011)
4.	Ramos, Adriana: 1 article (06/2011)
5.	Requena, Jesús R: 1 article (06/2011)
6.	Silva, Christopher J: 1 article (06/2011)
7.	Vázquez-Fernández, Ester: 1 article (06/2011)
8.	James, William: 1 article (04/2005)
9.	Tahiri-Alaoui, Abdessamad: 1 article (04/2005)

Related Diseases

1.	Fatal Familial Insomnia 11/20/1998 - "To test this hypothesis, we characterized the recombinant variants of human PrP(90-231) containing point mutations corresponding to Gerstmann-Straussler-Scheinker disease (P102L), Creutzfeld-Jakob disease (E200K), and fatal familial insomnia (M129/D178N). "
2.	Prion Diseases (Transmissible Spongiform Encephalopathies) 04/01/2005 - "Here we analyze the in vitro kinetics of amyloid formation from recombinant human PrP(90-231) in vitro in the context of two common allelic forms of PrP found in human populations that are associated with differences in prion disease susceptibility and pathological phenotype. "
3.	Gerstmann-Straussler-Scheinker Disease 11/20/1998 - "To test this hypothesis, we characterized the recombinant variants of human PrP(90-231) containing point mutations corresponding to Gerstmann-Straussler-Scheinker disease (P102L), Creutzfeld-Jakob disease (E200K), and fatal familial insomnia (M129/D178N). "
4.	Scrapie 06/07/2011 - "We used two chemical modifiers, tetranitromethane (TNM) and acetic anhydride (Ac(2)O), which specifically target accessible tyrosine and lysine residues, respectively, to modify recombinant Syrian hamster PrP(90-231) [rSHaPrP(90-231)] and SHaPrP 27-30, the proteinase K-resistant core of PrP(Sc) isolated from brain of scrapie-infected Syrian hamsters. "

Related Drugs and Biologics

1.	Endopeptidase K (Proteinase K)
2.	Tyrosine (L-Tyrosine)
3.	Tetranitromethane
4.	Lysine (L-Lysine)
5.	Amyloid (Amyloid Fibrils)
6.	acetic anhydride