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alpha-conotoxin Vc1.1

Also Known As:

Vc1.1 alpha-conotoxin

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Mollusk Venoms: 21
    - Conotoxins: 172
      - alpha-conotoxin Vc1.1: 5
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Mollusk Venoms: 21
      - Conotoxins: 172
        alpha-conotoxin Vc1.1: 5
  - Marine Toxins: 124
    - Mollusk Venoms: 21
      - Conotoxins: 172
        alpha-conotoxin Vc1.1: 5

Experts

1.	Down, John: 2 articles (12/2006 - 10/2005)
2.	Gayler, Ken R: 2 articles (12/2006 - 05/2004)
3.	Khalil, Zeinab: 2 articles (12/2006 - 10/2005)
4.	Livett, Bruce G: 2 articles (12/2006 - 05/2004)
5.	Sandall, David W: 2 articles (12/2006 - 05/2004)
6.	Satkunanathan, Narmatha: 2 articles (12/2006 - 10/2005)
7.	Adams, D J: 1 article (12/2007)
8.	Christie, M J: 1 article (12/2007)
9.	Clark, R J: 1 article (12/2007)
10.	Craik, D J: 1 article (12/2007)

Related Diseases

1.	Pain (Aches) 10/19/2005 - "This study shows that alpha-conotoxin Vc1.1, a neuronal nAChR antagonist, suppressed mechanical pain responses associated with peripheral neuropathy in rats in vivo and accelerated functional recovery of the injured neurones. " 10/19/2005 - "This paper demonstrates the capacity of the neuronal nicotinic acetylcholine receptor (nAChR) antagonist alpha-conotoxin Vc1.1 to inhibit pain responses in vivo. " 05/01/2004 - "We report that vc1a, the native form of alpha-conotoxin Vc1.1 (an unmodified 16 amino acid residue peptide that has notable pain-relieving capabilities), includes a hydroxyproline and a gamma-carboxyglutamate residue. "
2.	Peripheral Nervous System Diseases (PNS Diseases) 10/19/2005 - "This study shows that alpha-conotoxin Vc1.1, a neuronal nAChR antagonist, suppressed mechanical pain responses associated with peripheral neuropathy in rats in vivo and accelerated functional recovery of the injured neurones. "
3.	Neuralgia (Stump Neuralgia) 12/01/2006 - "Alpha conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurons. " 10/19/2005 - "Alpha-conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurones." 12/01/2007 - "The synthetic alpha-conotoxin Vc1.1 is a small disulfide bonded peptide currently in development as a treatment for neuropathic pain. " 08/11/2006 - "The alpha-conotoxin Vc1.1 is a small disulfide-bonded peptide currently in development as a treatment for neuropathic pain. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Disulfides
3.	1-Carboxyglutamic Acid (1 Carboxyglutamic Acid)
4.	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
5.	Hydroxyproline (4 Hydroxyproline)
6.	Amino Acids