dextromethorphan - quinidine combination

for the treatment of pseudobulbar affect in ALS, the combination of 30 mg DM and 30 mg Q is referred to as AVP-923, Note: Neurodex is a multimeaning Tradename

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Olney, Nicholas: 1 article (04/2010)
2.	Rosen, Howard: 1 article (04/2010)

Related Diseases

1.	Multiple Sclerosis 04/01/2010 - "A subsequent phase III clinical trial assessing a lower dose of AVP-923 (20 or 30 mg DM/10 mg Q) for the treatment of PBA in patients with ALS or multiple sclerosis was implemented by AVANIR and demonstrated a favorable safety profile of AVP-923 while maintaining efficacy. " 01/01/2005 - "Medison Pharma (Israel) has obtained development, marketing and distribution rights to the dextromethorphan/quinidine combination for the treatment of emotional lability in patients with multiple sclerosis in Israel. "
2.	Peripheral Nervous System Diseases (PNS Diseases) 04/01/2010 - "AVANIR Pharmaceuticals Inc, under license from Irisys Research & Development, is developing AVP-923 (Zenvia, Neurodex) for the treatment of pseudobulbar affect (PBA; in collaboration with Medison Pharma Ltd) and neuropathic pain associated with diabetic peripheral neuropathy. "
3.	Neuralgia (Stump Neuralgia) 04/01/2010 - "AVP-923, a combination of dextromethorphan hydrobromide and quinidine sulfate for the treatment of pseudobulbar affect and neuropathic pain." 04/01/2010 - "AVANIR Pharmaceuticals Inc, under license from Irisys Research & Development, is developing AVP-923 (Zenvia, Neurodex) for the treatment of pseudobulbar affect (PBA; in collaboration with Medison Pharma Ltd) and neuropathic pain associated with diabetic peripheral neuropathy. "
4.	Nervous System Diseases (Neurological Disorders) 04/01/2010 - "PBA, the main indication of AVP-923, is a neurological disorder characterized by uncontrollable and unpredictable episodes of laughing and/or crying. "

Related Drugs and Biologics

1.	dextromethorphan - quinidine combination
2.	Quinidine (Chinidin)
3.	Dextromethorphan (Racemethorphan)