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1- (2- hydroxy- 5- methylphenyl)- 3- phenyl- 1,3- propanedione

structure in first source

Also Known As:

HMDB compound

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - 1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione: 2
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Propane: 265
        1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione: 2

Experts

1.	Pan, Min-Hsiung: 2 articles (08/2016 - 11/2005)
2.	Chen, Wei-Jen: 1 article (08/2016)
3.	Hong, Hui-Mei: 1 article (08/2016)
4.	Hsu, Li-Sung: 1 article (08/2016)
5.	Huang, Hsiu-Chen: 1 article (08/2016)
6.	Lin, Chih-Li: 1 article (08/2016)
7.	Tsai, Jie-Heng: 1 article (08/2016)
8.	Ho, Chi-Tang: 1 article (11/2005)
9.	Lai, Ching-Shu: 1 article (11/2005)
10.	Lin, Jen-Kun: 1 article (11/2005)

Related Diseases

1.	Neoplasms (Cancer) 08/05/2016 - "The natural agent, 1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione (HMDB), has been reported to have growth inhibitory effects on several human cancer cells. " 11/16/2005 - "Here, we report that 1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione (HMDB) induces growth inhibition of human cancer cells and induction of apoptosis in A431 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). "
2.	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/05/2016 - "1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione Induces G1 Cell Cycle Arrest and Autophagy in HeLa Cervical Cancer Cells."
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/16/2005 - "Induction of apoptosis by 1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione through reactive oxygen species production, GADD153 expression, and caspases activation in human epidermoid carcinoma cells."

Related Drugs and Biologics

1.	Caspases
2.	Reactive Oxygen Species (Oxygen Radicals)