iododiflunisal

an amyloid inhibitor; structure in first source

Networked: 4 relevant articles (2 outcomes, 0 trials/studies)

1.	Arsequell, Gemma: 4 articles (01/2020 - 01/2014)
2.	Cardoso, Isabel: 3 articles (01/2020 - 01/2014)
3.	Valencia, Gregorio: 3 articles (01/2019 - 01/2014)
4.	Cossío, Unai: 2 articles (01/2020 - 01/2019)
5.	Cotrina, Ellen Y: 2 articles (01/2020 - 01/2019)
6.	Gómez-Vallejo, Vanessa: 2 articles (01/2020 - 01/2019)
7.	Jiménez-Barbero, Jesús: 2 articles (01/2020 - 01/2019)
8.	Llop, Jordi: 2 articles (01/2020 - 01/2019)
9.	Quintana, Jordi: 2 articles (01/2020 - 01/2019)
10.	Rios, Xabier: 2 articles (01/2020 - 01/2019)

1.	Alzheimer Disease (Alzheimer's Disease) 01/01/2019 - "We have previously shown that treatment of Alzheimer's Disease (AD) model mice with iododiflunisal (IDIF), a TTR tetramer stabilizing compound, prevents AD pathologies. " 01/01/2020 - "We monitored the therapeutic efficacy of two TTR stabilizers, iododiflunisal (IDIF), which acts as small-molecule chaperone of the TTR/Aβ interaction, and tolcapone, which does not behave as a small-molecule chaperone, in an animal model of Alzheimer's disease using positron emission tomography (PET). " 01/01/2020 - "Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1." 01/01/2014 - "Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model."
2.	Transthyretin-Related Hereditary Amyloidosis 01/12/2015 - "Tuning transthyretin amyloidosis inhibition properties of iododiflunisal by combinatorial engineering of the nonsalicylic ring substitutions."