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RWJ-69442

alpha-1A-adrenergic receptor antagonist; structure in first source

Also Known As:

(S)-2-(4-(dimethylamino)phenyl)-2,3-dihydro-N-(2-hydroxy-3-(4-(2-(1-methylethoxy)phenyl)-1-piperazinyl)propyl)-1,3-dioxo-1-H-isoindole-5-carboxamide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - Phthalimides: 12
        RWJ-69442: 1
- Imides: 79
  - Phthalimides: 12
    - RWJ-69442: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - RWJ-69442: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - Phthalimides: 12
        RWJ-69442: 1

Experts

1.	Kuo, G H: 1 article (01/2005)
2.	McKown, L A: 1 article (01/2005)
3.	Wu, W N: 1 article (01/2005)

Related Diseases

1.	Dehydration (Water Stress) 01/01/2005 - "The metabolic pathways for RWJ-69442 are proposed via the 4 steps: 1. phenyl/piperazinylhydroxylation, 2. N/O-dealkylation, 3. N-dephenylation, and 4. dehydration. "