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2- ((2'- amino)propionyl)aminobicyclo(3.1.0)hexane- 2,6- dicarboxylic acid

a prodrug of LY354740; a group II mGlu receptor agonist; structure in first source

Also Known As:

LY 544344; LY-544344; LY544344

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Alanine: 4133
    - 2-((2'-amino)propionyl)aminobicyclo(3.1.0)hexane-2,6-dicarboxylic acid: 2
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Bridged-Ring Compounds: 1
      - Bridged Bicyclo Compounds
        2-((2'-amino)propionyl)aminobicyclo(3.1.0)hexane-2,6-dicarboxylic acid: 2
Polycyclic Compounds: 6
- Bridged-Ring Compounds: 1
  - Bridged Bicyclo Compounds
    - 2-((2'-amino)propionyl)aminobicyclo(3.1.0)hexane-2,6-dicarboxylic acid: 2

Experts

1.	Hart, John C: 1 article (02/2006)
2.	Johnson, Bryan G: 1 article (02/2006)
3.	Knitowski, Karen M: 1 article (02/2006)
4.	McKinzie, David L: 1 article (02/2006)
5.	Perkins, Everett J: 1 article (02/2006)
6.	Rorick-Kehn, Linda M: 1 article (02/2006)
7.	Schoepp, Darryle D: 1 article (02/2006)
8.	Danysz, Wojciech: 1 article (09/2005)

Related Diseases

1.	Psychotic Disorders (Schizoaffective Disorder) 02/01/2006 - "Furthermore, we compare the oral efficacy of the mGlu2/3 receptor agonist LY354740 and its prodrug LY544344 [(1S,2S,5R,6S)-2-[(2'S)-(2'-amino)propionyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid hydrochloride] in rodent models of psychosis and anxiety. "
2.	Anxiety Disorders (Anxiety Disorder) 09/01/2005 - "Eli Lilly and Co is developing LY-544344, a prodrug of the metabotropic glutamate receptor 2/3 agonist LY-354740, for the potential treatment of anxiety disorders."

Related Drugs and Biologics

1.	Prodrugs
2.	eglumetad
3.	Hexanes
4.	Acids
5.	metabotropic glutamate receptor 2