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S 3304

structure in first source

Also Known As:

S-3304; S3304 cpd

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - S 3304: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - S 3304: 2
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiophenes: 257
    - S 3304: 2

Experts

1.	Bukowski, Ronald: 1 article (04/2007)
2.	Chiappori, Alberto A: 1 article (04/2007)
3.	Creaven, Patrick J: 1 article (04/2007)
4.	Eckhardt, S Gail: 1 article (04/2007)
5.	Ikeda, Minoru: 1 article (04/2007)
6.	Javle, Milind M: 1 article (04/2007)
7.	Kambayashi, Yoshikaze: 1 article (04/2007)
8.	Mekhail, Tarek: 1 article (04/2007)
9.	O'bryant, Cindy L: 1 article (04/2007)
10.	Sullivan, Daniel M: 1 article (04/2007)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2007 - "Patients had tumor biopsies before and after S-3304 administration and were also evaluated for response and survival. " 04/01/2007 - "A phase I pharmacokinetic and pharmacodynamic study of s-3304, a novel matrix metalloproteinase inhibitor, in patients with advanced and refractory solid tumors." 04/01/2007 - "The aims of this phase I clinical trial were to determine the maximum tolerated dose, dose-limiting toxicities, pharmacokinetic profile, and intratumoral MMP inhibitory activity of single-agent S-3304 in advanced and refractory solid tumors. "
2.	Myalgia 06/01/2005 - "Adverse events reported in the multiple dose treatment with S-3304 or placebo were mostly of mild severity, except for two episodes of moderate headache and two episodes of moderate myalgia. "
3.	Headache (Headaches) 06/01/2005 - "Most commonly reported adverse events in the multiple treatments with S-3304 were headache and somnolence. " 06/01/2005 - "Adverse events reported in the multiple dose treatment with S-3304 or placebo were mostly of mild severity, except for two episodes of moderate headache and two episodes of moderate myalgia. "
4.	Sleepiness 06/01/2005 - "Most commonly reported adverse events in the multiple treatments with S-3304 were headache and somnolence. "

Related Drugs and Biologics

1.	Matrix Metalloproteinase Inhibitors
2.	Matrix Metalloproteinases (MMPs)