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HS-1199

Synthetic chenodeoxycholic acid derivative with anticancer effect on malignant glioblastoma cells

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Bile Acids and Salts: 11432
      - Cholic Acids: 14
        Deoxycholic Acid: 963
        Chenodeoxycholic Acid: 877
        HS-1199: 7
    - Cholanes
      - Cholic Acids: 14
        Deoxycholic Acid: 963
        Chenodeoxycholic Acid: 877
        HS-1199: 7

Experts

1.	Kim, Nam Deuk: 5 articles (11/2005 - 09/2003)
2.	Suh, Hongsuk: 5 articles (11/2005 - 09/2003)
3.	Yoo, Young Hyun: 5 articles (11/2005 - 09/2003)
4.	Choi, Yung Hyun: 3 articles (11/2005 - 09/2003)
5.	Moon, Bongkyung: 2 articles (04/2004 - 12/2003)
6.	Mikov, Momir: 1 article (01/2019)
7.	Šarenac, Tanja: 1 article (01/2019)
8.	Choi, Sang-Ho: 1 article (11/2005)
9.	Im, Eunok: 1 article (11/2005)
10.	Baek, Soo Jin: 1 article (09/2005)

Related Diseases

1.	Glioblastoma (Glioblastoma Multiforme) 09/01/2005 - "This study was undertaken to explore whether synthetic CDCA derivatives, HS-1199 and HS-1200, had an anticancer effect on malignant glioblastoma cells. "
2.	Colonic Neoplasms (Colon Cancer) 07/01/2004 - "In the present study, the effects of the synthetic derivatives of ursodeoxycholic acid (UDCA), HS-1030 and HS-1183, and chenodeoxycholic acid (CDCA), HS-1199 and HS-1200, on the proliferation of HT-29 human colon cancer cells were investigated. "
3.	Stomach Neoplasms (Stomach Cancer) 04/01/2004 - "The human stomach cancer cell line, SNU-1, cells were treated with the synthetic CDCA derivatives, HS-1199 and HS-1200. " 12/01/2003 - "Apoptosis-inducing activity of synthetic CDCA derivatives, HS-1199 and HS-1200, on gastric cancer cell line SNU-1 cells was explored. " 04/01/2004 - "The CDCA derivatives, HS-1199 and HS-1200, both induced apoptosis of the SNU-1 gastric cancer cells in caspase- and mitochondria-dependent fashions. "
4.	Carcinoma (Carcinomatosis) 01/01/2019 - "In this scientific work, in addition to explaining the various treatments necessary for the treatment of cervical carcinoma, we were discussed about the anticancer effects of the synthetic derivative of ursodeoxycholic acid, such as HS-1183, and synthetic derivatives of chenodeoxycholic acid such as HS-1199 and HS-1200. " 09/25/2003 - "The effects of synthetic derivatives of ursodeoxycholic acid (UDCA), HS-1183, and chenodeoxycholic acid (CDCA), HS-1199 and HS-1200, on the proliferation of human prostate carcinoma PC-3 cells were investigated. "
5.	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/01/2019 - "The synthetic derivatives of ursodeoxycholic acid and chenodeoxycholic acid such as HS-1183, HS-1199, and HS-1200 are used to treat cervical cancer. "

Related Drugs and Biologics

1.	HS 1200
2.	Ursodeoxycholic Acid (Urso)
3.	Chenodeoxycholic Acid (Chenix)
4.	HS 1183
5.	HS 1030
6.	Caspases