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OR 1958

inhibits cytokine production and histamine release; an NSAID

Also Known As:

OR-1958; OR1958

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfhydryl Compounds: 4168
    - OR 1958: 1

Experts

1.	Eklund, Kari K: 1 article (01/2005)
2.	Laitinen, Charlotta: 1 article (01/2005)
3.	Mäki, Tiina: 1 article (01/2005)
4.	Nissinen, Erkki: 1 article (01/2005)
5.	Vainio, Petri J: 1 article (01/2005)
6.	Vendelin, Johanna: 1 article (01/2005)

Related Diseases

1.	Necrosis 01/01/2005 - "Polymerase chain reaction studies showed that OR-1958 attenuated the activation-induced increase of tumour necrosis factor-alpha mRNA in HMC-1 cells. " 01/01/2005 - "Orazipone, OR-1958 and budesonide inhibited significantly and dose dependently tumour necrosis factor-alpha production in HMC-1 cells with IC50-values of 20, 10, and 0.25 microM, respectively. "
2.	Chronic Obstructive Pulmonary Disease (COPD) 01/01/2005 - "Orazipone (OR-1384) and OR-1958 are novel anti-inflammatory sulfhydryl reactive compounds with potential applications in the treatment of chronic obstructive lung disease and colitis. "
3.	Colitis 01/01/2005 - "Orazipone (OR-1384) and OR-1958 are novel anti-inflammatory sulfhydryl reactive compounds with potential applications in the treatment of chronic obstructive lung disease and colitis. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Budesonide (Pulmicort)
3.	orazipone