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curcusone B

has antineoplastic activity; isolated from Jatropha curcas; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - curcusone B: 1

Experts

1.	Muangman, Surin: 1 article (01/2005)
2.	Thippornwong, Montri: 1 article (01/2005)
3.	Tohtong, Rutaiwan: 1 article (01/2005)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2005 - "Curcusone B, thus, effectively suppresses the metastatic processes at doses that are non-toxic to cells, which may be of therapeutic benefit for the treatment of metastatic cancers."
01/01/2005 - "Treatment with non-cytotoxic doses of curcusone B resulted in a strong reduction of in vitro invasion, motility and secretion of matrix-metalloproteinases (MMP) of the cancer cells, whereas the ability to adhere to a Matrigel-coated surface was variably sensitive to curcusone B treatment. "

Related Drugs and Biologics

1.	Matrix Metalloproteinases (MMPs)
2.	matrigel