periplocin

01/01/2021 - "Previous studies have shown that periplocin, a naturally occurring compound, inhibits growth and induces apoptosis in several cancers. "
06/05/2020 - "In this study, we investigated the effects of periplocin in two myxofibrosarcoma (MFS)cell lines, MUG-Myx2a and MUG-Myx2b, which are subclones of the same tumor and reflect the tumor´s heterogeneity, and in T60 primary myxofibrosarcoma cells. "
07/01/2023 - "Periplocin also inhibited the expression of CXCL1 and CXCL3, leading to decreased accumulation of MDSCs in HCC tumors. "
01/01/2022 - "Periplocin inhibits CFPAC1 xenograft tumor growth in nude mice and increases tumor cell autophagy. "
01/01/2022 - "Periplocin, a natural compound, has been shown to induce apoptosis in a variety of cancer cells. "

04/01/2019 - "Collectively, we lay the rationale for traditional usage for traumatic injury, suggesting that periplocin and periploca forrestii is a promising candidate for management of chronic wounds."

01/01/2021 - "MTS assay, flow cytometry, real-time quantitative polymerase chain reaction (qPCR), and Western blotting were used to verify whether periplocin possesses anti-lymphoma activity. "
01/01/2021 - "However, the effects of periplocin on lymphoma and the underlying mechanisms of action remain unclear. "
01/01/2021 - "Inhibitory Effects of Periplocin on Lymphoma Cells: A Network Pharmacology Approach and Experimental Validation."
01/01/2021 - "Periplocin showed anti-tumor effects in lymphoma cells through multiple targets and signaling pathways, and could be a novel therapeutic agent for the treatment of lymphoma."

02/01/2022 - "Periplocin ameliorates mouse age-related meibomian gland dysfunction through up-regulation of Na/K-ATPase via SRC pathway."

01/01/2022 - "This study is aimed to determine the effect of Periplocin treatment on autophagy in human pancreatic cancer cells, as well as the underlying mechanisms. "
01/01/2021 - "This study aimed at determining the effect of periplocin treatment on the apoptosis and proliferation of human pancreatic cancer cells, and to elucidate on its mechanisms of action. "
01/01/2022 - "Collectively, these results have shown that Periplocin promotes autophagy in human pancreatic cancer cells by regulating the AMPK/mTOR pathway."
01/01/2022 - "Pancreatic cancer cells were treated with different concentrations of Periplocin, and real-time cell analysis (RTCA), colony formation assay, and Ki67 immunofluorescence detection were used to determine cell proliferation. "
01/01/2022 - "Periplocin Induces Apoptosis of Pancreatic Cancer Cells through Autophagy via the AMPK/mTOR Pathway."