P2-246-259

synthetic P2-246-259 (RAEVSYVHVNGAKF) is a BALB/c mouse T-cell epitope of Cry j 2, which is a major Japanese cedar (Cryptomeria japonica) pollen allergen; symptoms and reactions of allergic rhinitis were significantly inhibited by oral administration of P2-246-259

Also Known As:

RAEVSYVHVNGAKF peptide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Epitopes: 19548
    - T-Lymphocyte Epitopes: 1675
      - P2-246-259: 1
  - Plant Antigens: 7
    - P2-246-259: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Plant Proteins: 334
    - Plant Antigens: 7
      - P2-246-259: 1

Experts

1.	Hirahara, Kazuki: 1 article (03/2005)
2.	Ito, Kazuhiro: 1 article (03/2005)
3.	Murasugi, Takako: 1 article (03/2005)
4.	Nakagami, Yasuhiro: 1 article (03/2005)
5.	Sakaguchi, Masahiro: 1 article (03/2005)
6.	Taniguchi, Yoshifumi: 1 article (03/2005)
7.	Yamashita, Makoto: 1 article (03/2005)
8.	Yoshitomi, Tomomi: 1 article (03/2005)

Related Diseases

Allergic Rhinitis

03/07/2005 - "These symptoms and reactions of allergic rhinitis were significantly inhibited by oral administration of P2-246-259. "
03/07/2005 - "These results indicate utility of mice as models for allergic rhinitis; furthermore, the effects of P2-246-259 on allergic rhinitis imply that oral administration of a T cell epitope is a promising approach for specific immunoprophylaxis."

Related Drugs and Biologics

1.	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)

Related Therapies and Procedures

1.	Oral Administration