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PD-198961

synthetic factor Xa inhibitor

Also Known As:

3-(4-5-((2R,6S)-2,6-dimethyltetrahydro-1(2H)-pyridinyl)pentyl-3-oxo-3,4-dihydro-2-quinoxalinyl)-4-hydroxybenzenecarboximidamide

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinoxalines: 324
      - PD-198961: 1

Experts

1.	Chi, Liguo: 1 article (10/2004)
2.	Edmunds, Jeremy J: 1 article (10/2004)
3.	Gibson, Glenn: 1 article (10/2004)
4.	Hicks, Gary: 1 article (10/2004)
5.	Janiczek, Nancy: 1 article (10/2004)
6.	Leadley, Robert: 1 article (10/2004)
7.	Mertz, Thomas E: 1 article (10/2004)
8.	Peng, Yun-Wen: 1 article (10/2004)
9.	Rapundalo, Stephen: 1 article (10/2004)

Related Diseases

1.

Thrombosis (Thrombus)

10/01/2004 - "PD-198961 dose dependently increased the time to occlusion (TTO), reduced thrombus weight (TW), and decreased the incidence of occlusion. "
10/01/2004 - "In an FeCl3-induced model of arterial thrombosis in rabbits, the antithrombotic effects of PD-198961 were compared with that of LB-30057, a direct thrombin inhibitor, and enoxaparin, a low molecular weight heparin (LMWH). "

Related Drugs and Biologics

1.	Enoxaparin (Lovenox)
2.	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)
3.	Antithrombins
4.	LB 30057