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estradiol-3,4-quinone

structure in first source

Also Known As:

E2-3,4-Q

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Estranes
      - Estrenes
        Estradiol: 14115
        estradiol-3,4-quinone: 5
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Gonadal Hormones: 716
    - Gonadal Steroid Hormones: 7657
      - Estradiol Congeners: 358
        Estradiol: 14115
        estradiol-3,4-quinone: 5

Experts

1.	Chen, Dar-Ren: 3 articles (01/2020 - 04/2013)
2.	Hsieh, Wei-Chung: 3 articles (01/2020 - 04/2013)
3.	Lin, Po-Hsiung: 3 articles (01/2020 - 04/2013)
4.	Lin, Che: 2 articles (01/2014 - 04/2013)
5.	Tsuang, Ben-Jei: 2 articles (01/2014 - 04/2013)
6.	Yu, Wen-Fa: 2 articles (01/2014 - 04/2013)
7.	Liao, Yi-Lun: 1 article (01/2020)
8.	Lin, Kuo-Juei: 1 article (01/2020)
9.	Wang, Yu-Fen: 1 article (01/2020)
10.	Tsai, Chen-His: 1 article (01/2014)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 01/01/2014 - "Taken together, this evidence lends further support to the theme that cumulative concentration of E2-3,4-Q is a significant predictor of the risk of breast cancer. " 04/26/2013 - "Overall, this evidence suggests that disparity in estrogen disposition and the subsequent elevation of cumulative body burden of E2-3,4-Q may play a role in the development of breast cancer." 01/01/2020 - "The findings of this study suggest that differences in the disposition of estrogen and naphthalene, and the subsequent elevation of cumulative E2-3,4-Q and 1,2-NPQ may serve as biomarkers of breast cancer risk."
2.	Neoplasms (Cancer) 01/01/2020 - "Compared with controls, levels of 1,2-NPQ and E2-3,4-Q were elevated by two- to ten-fold in cancer patients (p < 0.001). " 01/01/2006 - "The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity."
3.	Carcinogenesis 04/26/2013 - "Elevation of E2-3,4-Q to E2-2,3-Q ratio is thought to be an important indicator of estrogen-induced carcinogenesis. "
4.	Carcinoma (Carcinomatosis) 02/01/2002 - "To investigate the prostatic metabolism of estrogens, Noble rats were treated with the CE 4-hydroxyestradiol (4-OHE2) or estradiol-3,4-quinone (E2-3,4-Q), and CE metabolites and conjugates were analyzed in the four regions of the prostate, which differ in susceptibility to carcinoma formation. "

Related Drugs and Biologics

1.	Estrogens (Estrogen)
2.	Biomarkers (Surrogate Marker)
3.	naphthalene
4.	Indicators and Reagents (Reagents)
5.	DNA (Deoxyribonucleic Acid)
6.	estradiol-2,3-O-quinone
7.	4-hydroxyestradiol