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metafectene

liposomal reagent for gene delivery, superior to lipofectamine in the transfection of G(s) alpha prostate cancer cells

Networked: 10 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Lipids: 114793
- metafectene: 10

Experts

1.	Konopka, Krystyna: 5 articles (08/2014 - 01/2005)
2.	Overlid, Nathan: 4 articles (01/2009 - 01/2005)
3.	Gebremedhin, Senait: 2 articles (08/2014 - 01/2009)
4.	Düzgüneş, Nejat: 2 articles (01/2009 - 01/2006)
5.	Düzgünes, Nejat: 2 articles (12/2005 - 01/2005)
6.	Golkar, Nasim: 1 article (09/2016)
7.	Samani, Soliman Mohammadi: 1 article (09/2016)
8.	Tamaddon, Ali Mohammad: 1 article (09/2016)
9.	Bernt, William: 1 article (08/2014)
10.	Duzgunes, Nejat: 1 article (08/2014)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 10/01/2004 - "Metafectene is superior to lipofectamine in the transfection of G(s) alpha prostate cancer cells."
2.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/01/2009 - "Murine squamous cell carcinoma cells, SCCVII, mouse embryonic fibroblasts, NIH-3T3, and murine immortalized mammary cells, NMuMG, were transfected with Metafectene PRO at 2 microl/1 microg DNA. " 12/01/2005 - "In this study, the authors examined two novel gene transfection reagents, Metafectene and GeneJammer, for their ability to deliver a reporter gene to SCCVII murine squamous cell carcinoma cells in the presence of high concentrations of mouse serum. " 01/01/2006 - "Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells."
3.	Squamous Cell Carcinoma of Head and Neck 12/01/2005 - "The authors' observations suggest that Metafectene may be useful for the gene therapy of oral squamous cell carcinoma in a murine model involving the induction of oral tumors by SCCVII cells." 01/01/2005 - "In this study we evaluated the effect of high concentrations (20-60%) of fetal bovine serum (FBS) on the transfection efficiency of two novel reagents, the polycationic liposome, Metafectene, and the polyamine reagent, GeneJammer, in HSC-3 and H357 human oral squamous cell carcinoma (OSCC) cells. "
4.	Neoplasms (Cancer) 03/01/2006 - "pshRNA packaged by METAFECTENE was transfected into the transplantation tumors. " 12/01/2005 - "The authors' observations suggest that Metafectene may be useful for the gene therapy of oral squamous cell carcinoma in a murine model involving the induction of oral tumors by SCCVII cells." 01/01/2009 - "Human cancer cells (HeLa, KB, HSC-3, H357, H376, H413), oral keratinocytes, GMSM-K, and chemically immortalized human mammary cells, 184A-1, were transfected with Metafectene at 2 microl/1 microg DNA. "
5.	Mouth Neoplasms (Oral Cancer) 01/01/2005 - "Serum-resistant gene transfer to oral cancer cells by Metafectene and GeneJammer: application to HSV-tk/ganciclovir-mediated cytotoxicity." 01/01/2006 - "A relatively high efficiency of transfection could be achieved in human oral cancer cells transfected with the polycationic liposome, Metafectene, and the polyamine reagent, GeneJammer, in the presence of 60% fetal bovine serum (FBS) (Konopka et al., Cell. "

Related Drugs and Biologics

1.	Gs GTP-Binding Protein alpha Subunits (G(s)alpha)
2.	Lipofectamine
3.	Indicators and Reagents (Reagents)
4.	genejammer
5.	Liposomes (Liposome)
6.	Bovine Serum Albumin
7.	Polyamines
8.	DNA (Deoxyribonucleic Acid)
9.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
10.	Small Interfering RNA (siRNA)

Related Therapies and Procedures

1.	Transplantation