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delta(12)-prostaglandin J(2)

cyclopentenone PG known to elicit anti-neoplastic effects via apoptosis induction

Also Known As:

delta12-PGJ2

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins D: 1987
        Prostaglandin D2: 887
        delta(12)-prostaglandin J(2): 5
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins D: 1987
        Prostaglandin D2: 887
        delta(12)-prostaglandin J(2): 5

Experts

1.	Chiang, Po-Cheng: 1 article (08/2006)
2.	Fan, Jia-Rong: 1 article (08/2006)
3.	Guh, Jih-Hwa: 1 article (08/2006)
4.	Huang, Dong-Ming: 1 article (08/2006)
5.	Kung, Fan-Lu: 1 article (08/2006)
6.	Li, Tsai-Kun: 1 article (08/2006)
7.	Pan, Shiow-Lin: 1 article (08/2006)
8.	Shen, Ya-Ching: 1 article (08/2006)
9.	Berdo, Ingrid: 1 article (07/2004)
10.	Figueiredo-Pereira, Maria E: 1 article (07/2004)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2001 - "TEI-9826 exhibited nearly identical or greater potential antitumor activity compared to Delta12-PGJ2 and Delta7-PGA1 in vitro against Colon26 tumor cells. " 11/19/1998 - "Prostaglandin (PG) A2 (PGA2) and Delta12-PGJ2 have potent antiproliferative activity on various tumor cell growths in vitro. " 08/07/2006 - "Bromovulone III displayed anti-tumor activity of 30 to 100 times more effective than PGA1, PGA2 and delta12-PGJ2 in PC-3 cells. " 08/07/2006 - "Cyclopentenone prostaglandins (PGs) such as PGA1, PGA2 and delta12-PGJ2 have been shown to suppress tumor cell growth and to induce apoptosis in prostate cancer cells. "
2.	Prostatic Neoplasms (Prostate Cancer) 08/07/2006 - "Cyclopentenone prostaglandins (PGs) such as PGA1, PGA2 and delta12-PGJ2 have been shown to suppress tumor cell growth and to induce apoptosis in prostate cancer cells. "
3.	Inflammation (Inflammations) 07/09/2004 - "In conclusion, impairment of ubiquitin hydrolase activity, such as triggered by Delta12-PGJ2, may be an important contributor to neurodegeneration associated with accumulation of ubiquitinated proteins and inflammation."
4.	Hepatocellular Carcinoma (Hepatoma) 06/24/1999 - "We have examined specific genes whose expression is altered during apoptosis induced by prostaglandin (PG)A2 and Delta12-PGJ2 in human hepatocellular carcinoma Hep3B cells. "

Related Drugs and Biologics

1.	Prostaglandins
2.	prostaglandin A2 (PGA2)
3.	Ubiquitinated Proteins
4.	Ubiquitin
5.	Hydrolases
6.	bromovulone III
7.	TEI9826
8.	prostaglandin A1 (PGA1)
9.	cyclopentenone