hydroxyapatite-polylactide

a ceramic/polymer composite, whose application as a resorbable biomaterial for the substitution and repair of hard bone tissue is widely promising in orthopedic, oral, maxillofacial, and reconstructive surgery

Also Known As:

HAp-PLLA; hydroxyapatite-poly-L-lactide

Networked: 10 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Polyesters: 921
    - hydroxyapatite-polylactide: 10
Biomedical and Dental Materials
- Polymers: 13051
  - Polyesters: 921
    - hydroxyapatite-polylactide: 10
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Polyesters: 921
        hydroxyapatite-polylactide: 10
Inorganic Chemicals: 9

Experts

1.	Furukawa, Taizo: 2 articles (03/2006 - 08/2003)
2.	Ishii, Shinsuke: 2 articles (03/2006 - 08/2003)
3.	Matsusue, Yoshitaka: 2 articles (03/2006 - 08/2003)
4.	Nakamura, Takashi: 2 articles (03/2006 - 08/2003)
5.	Okuno, Masaki: 2 articles (03/2006 - 08/2003)
6.	Shikinami, Yasuo: 2 articles (03/2006 - 08/2003)
7.	Tamura, Jiro: 2 articles (03/2006 - 08/2003)
8.	Furukawa, T: 2 articles (06/2000 - 05/2000)
9.	Matsusue, Y: 2 articles (06/2000 - 05/2000)
10.	Nakamura, T: 2 articles (06/2000 - 05/2000)

Related Diseases

1.	Bone Fractures (Bone Fracture) 03/01/2006 - "A 5-7 year in vivo study of high-strength hydroxyapatite/poly(L-lactide) composite rods for the internal fixation of bone fractures." 08/15/2003 - "Long-term study of high-strength hydroxyapatite/poly(L-lactide) composite rods for the internal fixation of bone fractures: a 2-4-year follow-up study in rabbits." 06/05/2000 - "Histomorphometric study on high-strength hydroxyapatite/poly(L-lactide) composite rods for internal fixation of bone fractures." 02/09/2016 - "It implied that g-HAP/PLLA composites might be a candidate for human non-load bearing bone fracture fixation which needs high initial strength and fast degradation rate. " 05/01/2000 - "Biodegradation behavior of ultra-high-strength hydroxyapatite/poly (L-lactide) composite rods for internal fixation of bone fractures."
2.	Osteoporosis 10/01/2005 - "Repair of bone tissue affected by osteoporosis with hydroxyapatite-poly-L-lactide (HAp-PLLA) with and without blood plasma." 10/01/2005 - "The aim of this study is to examine the reparatory ability of the synthetic biomaterial hydroxyapatite-poly-L-lactide (HAp-PLLA), the replacement of alveolar ridge, and rehabilitation of bone defects caused by osteoporosis, in an experimental group of animals. "
3.	Comminuted Fractures 06/01/2020 - "We describe a case series treated using hydroxyapatite/poly-L-lactide (HPLLA) threaded pins, which are not only bioabsorbable, but also osteoconductive, for osteosynthesis in crushed amputation or comminuted fracture, including distal phalanx amputation. "
4.	Shoulder Fractures 07/08/2023 - "Endosteal strut using a hydroxyapatite/poly-L-lactide mesh tube with a proximal humeral locking plate for the treatment of proximal humeral fractures."
5.	Melanoma (Melanoma, Malignant) 08/01/2013 - "We have measured the interaction forces between a murine melanoma cell and a poly(l-lactic acid) (PLLA) microsphere coated with/without hydroxyapatite (HAp) nanoparticles (i.e., an HAp/PLLA or a bare PLLA microsphere) in a serum-free culture medium, using atomic force microscopy (AFM) with colloid probe technique, in order to investigate how the HAp-nanoparticle coating as well as interfacial serum proteins influence the cell-microsphere adhesion. "

Related Drugs and Biologics

1.	hydroxyapatite-polylactide
2.	Biocompatible Materials (Biomaterials)
3.	Durapatite (Hydroxylapatite)
4.	Colloids (Colloid)
5.	Blood Proteins (Serum Proteins)
6.	poly(lactide) (polylactic acid)

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Surgical Amputation (Amputations)